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OVD influences
This prospective case series provides data on a previously uninvestigated area. Eyes due to have routine phakoemulsification were divided into six groups according to ophthalmic viscosurgical device (OVD) type. After cataract extraction aphasic refraction using intraoperative aberrometry with the ocular...
Corneal molecular and cellular biology for refractive surgeon
This is an interesting literature review that looks into the recent advances concerning the corneal molecular and cellular processes that are involved in the wound healing response after excimer laser surface ablation and LASIK surgery. It talks about the complex...
Tocilizumab in Graves’ orbitopathy
This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience
Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...
Use of control scores for intermittent exotropia
This study surveyed paediatric ophthalmologists to determine their use of the Newcastle, PEDIG and LACTOSE control scores in the diagnosis and management of intermittent exotropia. The authors aimed to identify how frequently control scores are used clinically, the barriers to...
Surgical treatment outcomes and predictors for consecutive exotropia
This retrospective study presented the long-term results of consecutive exotropia surgery and its prognostic factors, and compared efficacy of medial rectus advancement, lateral rectus recession, or a combination of both. Patients were treated between 2000–2020. Mean age was 33.98 ±17.68...
Neurogenic palsy due to COVID-19
The authors aimed to identify cases of neurogenic palsy in the presence of Covid-19 and document the patient characteristics, type of palsy and possible aetiologies. Case reports and case series were included in the search. Twenty-three articles were included with...
Comparison of false-negative responses in glaucoma patients and normal observers
The authors compared false negative rates for full threshold (FULL) and Swedish Interactive Threshold Algorithm (SITA) standard automated perimetry in healthy control subjects and glaucoma patients. Twenty-four subjects underwent visual field testing of one eye five times within six weeks...
Use of white coat and greetings
This study was undertaken to characterise the practice patterns of paediatric ophthalmologists regarding their use of white coats and salutations in outpatient visits. A questionnaire was sent to American Association for Pediatric Ophthalmology and Strabismus (AAPOS) members with a response...
Enzymatic clearance of anterior chamber infiltrate in uveitis
Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...
