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Topical atorvastatin for dry eye and blepharitis
Dry eye is a very common problem with 20% of the population affected and is frequently associated with blepharitis (DEB), which has an over prevalence of about 40%. The aim of this study was to evaluate a topical atorvastatin formulation...
Cytotoxic effect of voriconazole on human corneal epithelial cells
Voriconazole is a second-generation synthetic derivative of fluconazole with broadened antifungal spectrum. It is becoming the drug of choice for fungal keratitis. Voriconazole eye drops are not available commercially, thus have to be prepared by diluting the intravenous formulation containing...
Sustained elevation of extracellular ATP in chronic glaucoma
Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...
Postural control in glaucoma patients with virtual reality
The authors report on a cross-sectional study evaluating postural control and history of falls in glaucoma patients. History of falls was obtained using the Falls Screening and Referral Algorithm. Postural stability was assessed using a force platform under four conditions:...
A case series of acquired esotropia in cerebellar disease
Acquired esotropia in cerebellar disease is well described but under-recognised. The pathogenesis of cerebellar esotropia is controversial. It is suggested it may be a result of disruption to central vestibular pathways. This article reports a case series of seven adults...
A case of progressive supranuclear palsy-like syndrome following aortic aneurysm repair
This original article illustrates the case of an 18-year-old woman who developed progressive supranuclear palsy-like syndrome following an uneventful aortic aneurysm repair. The patient was unaffected for the first 48 hours after surgery and then developed dysarthria, dysphagia (requiring a...
Neuro-ophthalmological symptoms in patients with cerebral venous sinus thrombosis
The authors of this article have evaluated the neuro-ophthalmological symptoms of 49 patients with cerebral venous sinus thrombosis. They have evaluated the onset of the disease as well as the symptoms reported. The authors present extensive clinical information for individual...
A case series of acute visual loss following excessive alcohol and / or drug use
This study presents three cases of so called Saturday night retinopathy, an acute visual loss following intravenous drug abuse and stupor, leading to continuous pressure on the orbit while asleep. All three cases presented with acute vision loss and had...
Conjunctival melanoma involving the lacrimal drainage system
A total of 52 patients were diagnosed with conjunctival melanoma over a period of 17 years, 17 of whom required orbital exenteration. Five of these were found to have melanoma involving the lacrimal drainage apparatus (LDA). One was evident clinically...
Botulinum toxin after orbicularis myectomy
This is a retrospective review of 27 patients with benign essential blepharospasm who had become resistant to treatment with botulinum toxin and had therefore undergone orbicularis myectomy of the upper lids. The study compares the dose and frequency of botulinum...
Screening for ROP using wide-angle digital retinal photography by non-ophthalmologists
This is a systematic review article to evaluate the accuracy of digital retinal photography (DRP) performed by trained personnel (non-ophthalmologists) in diagnosing clinically significant retinopathy of prematurity (ROP). The authors used search engines including Medline, EMBASE, CINAHL and Cochrane databases....
