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Complement Factor H and Factor H-Like protein are expressed in human RPE cells
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...
HtrA1 enhances cell senescence
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...Getting one’s eye in
Lisette Bijma, Sister in the Eye Emergency Department at John Radcliffe Hospital, explains how COVID-19 provided a ‘baptism by fire’ and enabled fundamental and positive changes to the running of the department. Five years ago, I arrived in the UK,...Hot debates in medical retina and imaging: Perspectives from the Controversies in Ophthalmology 2020 virtual conference
Controversies in medical retina and imaging were debated during the Controversies in Ophthalmology 2020 virtual conference held during two mid-day scientific sessions on 27 and 28 March 2020. The author recounts key perspectives and presents viewpoint recommendations from the Vision...Strengthening diabetic retinopathy services in Nigeria through DR-NET – from grass roots to national policy development
This is the third article in a series (see Part 1 and Part 2) reflecting on how shared learning via networks of UK and international eye health professionals is contributing to reducing unnecessary blindness in Nigeria. Earlier articles focused on...University of Glasgow officially opens new home for School of Health & Wellbeing
Research in the Clarice Pears building aims to improve health and reduce health inequalities.£5 million award for world-leading research facilities within new eye health centre
The Sir Jules Thorn Charitable Trust has awarded £5 million to UCL in partnership with Moorfields Eye Charity and Moorfields Eye Hospital to support Oriel – a centre for advancing eye health, opening in 2027.
Use of botulinum toxin A in the treatment of intermittent exotropia
In this prospective cohort study, the authors aimed to evaluate the efficiency of botulinum toxin A (BTA) injection in the treatment of intermittent exotropia (IXT) and examine factors affecting treatment outcomes. Seventy-four patients diagnosed with any type of IXT were...
Suture-less flanged IOL fixation vs. conventional sutured SF in IOL dislocation
The authors report the analysis of a prospective, comparative cohort study on 103 consecutive patients (103 eyes) with intraocular lens (IOL) dislocation who underwent vitrectomy with IOL removal and sutured scleral fixation (SF) (53 eyes) or flanged IOL fixation (50...
The evolution and visual prognosis of glial proliferation of different grades after macular hole surgery
This retrospective research study aimed to investigate the evolution of glial proliferation of varying grades after successful idiopathic macular hole repair and its effects on foveal microstructure and best-corrected visual acuity (BCVA). Two-hundred and two eyes were enrolled in this...What's trending Oct/Nov 2023
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #Hello A big hello to those reading. It’s my absolute pleasure to take on the mantel of section editor of the...
