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Cataract in patients with pseudoexfoliation syndrome
The authors present a prospective comparative study in 43 patients with (group 1) or without (group 2) pseudoexfoliation (PXF) undergoing cataract surgery. Anterior capsule samples were obtained in all patients and analysed for signs of apoptosis by using special staining...
Optical quality difference between monofocal and multifocal intraocular lenses
It is well known that multifocal intraocular lenses (IOLs) can generate more than one focus to restore distance and near vision, but patients may experience adverse optical phenomena such as decreased contrast sensitivity and induced glare or halos. The authors...
Phakic iris clip lenses and endothelial cell loss
This retrospective observational study included long-term results on endothelial cell losses in highly myopic eyes, which underwent phakic iris-clip lens implantations. Included in the analysis were 113 eyes with mean preoperative spherical equivalent (SEQ) of -14.67 +/- 5.15 Diopters (D)....
MicroRNA inhibits corneal neovascularisation
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
Corneal stroma modelling under hypoxic conditions
The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...
Diagnosis of amiodarone-associated optic neuropathy
Amiodarone is a widely used anti-arrhythmic drug. Several case reports describe optic neuropathy which has been linked to its use. This case series discusses the diagnosis of amiodarone-associated optic neuropathy (AAON) and its potential impact on cardiac therapy. The authors...
An atypical presentation of Vogt-Koyanagi-Harada Disease
The authors present a single case of atypical presentation of Vogt-Koyanagi-Harada disease. A 42-year-old female presented with unilateral visual loss associated with systemic symptoms of fever and headache. Initial ophthalmic examination revealed a unilateral neuroretinitis, however, investigations for infectious and...
Overview of traumatic optic neuropathy
The authors present the clinical features and role of various treatment modalities on the final vision outcome in traumatic optic neuropathy (TON). They retrospectively reviewed the records of patients with a diagnosis of TON over a four year period in...
A case of post-viral ocular microflutter
A number of eye movements disrupt visual fixation, one such movement being saccadic intrusions which are described as small involuntary saccadic movements. Among saccadic intrusions without intersaccadic intervals, ocular flutter and opsoclonus are prominent. When the saccadic amplitude is very...
PROMs in blepharoplasty
With the advent of clinical commissioning in NHS England the need to demonstrate the benefits of certain surgeries is becoming increasing common. Upper Lid blepharoplasty is a commonly performed operation and often seen as a cosmetic procedure. Danish visitation guidelines...
PD-1 and PD-L1 in exenteration specimens
This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...
