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A mouse model for uveal melanoma

1 December 2014 | | Ocular Pathology and Oncology | Grm1, melanoma, metabotropic glutamate receptor, mouse model, uveal melanoma
Uveal melanoma (UM) is the most common malignant tumour arising within the eye and is a severe threat for both sight and life, due to a high risk of metastasis. There are no animal models of UM, but the Tg(Grm1)...

Pterygium ocular surface temperature

1 August 2014 | | Cornea / External Eye Disease
This prospective study investigated the ocular surface temperature in patients with pterygia compared to those with dry and healthy eyes respectively. Previous studies have shown that patients with dry eyes show a significant decrease in ocular surface temperature on sustained...

Identification and diagnosis of thalamic haemorrhage

1 August 2014 | | Neuro-Ophthalmology | Eye movements, neuro-ophthalmology, thalamic haemorrhage
This paper presents a case of thalamic haemorrhage and discusses clinical findings, providing valuable insight into signs clinicians need to look for. The case presented is of a 76-year-old female who developed left hemiplegia and hemi anaesthesia. Ocular motility testing...

Translucent vs. lightproof occluders

1 February 2014 | | Paediatric Ophthalmology / Strabismus
This study investigates the change in visual acuity following occlusion in amblyopes and non-amblyopes using translucent versus lightproof occlusion of the dominant eye. Group 1 non-amblyopes consisted of 26 subjects: 16 visually normal and 10 strabismic or anisometropic subjects without...

Contrast sensitivity comparisons for Pelli Robson, Hiding Heidi and Double Happy tests

3 June 2024 | | Paediatric Ophthalmology / Strabismus
The authors aimed to compare contrast thresholds and measure agreement across current paediatric assessment of contrast sensitivity with Hiding Heidi and Double Happy contrast sensitivity tests vs. the gold-standard Pelli Robson chart. Reduced contrast levels were similar under different light...
JAAPOS journal cover image.

Use of oral fluorescein angiography in a paediatric population

1 July 2024 | | Paediatric Ophthalmology / Strabismus
The authors report a retrospective records review of all patients who received an oral ultrawide fluorescein angiography (FA) over a 42-month period at a single children’s hospital. Data were extracted from the records including indication for FA, adverse events, pauses...

What's trending Dec/Jan 2020

2 December 2019 | | Ophthalmology, Retina / Uvea / Vitreous, Cataract and Refractive
#eyedoctor #banned #visamix-up #HomeOffice #hostileenvironment An ophthalmologist was left stranded overseas when the Home Office refused him entry due to a visa mix-up. Dr Chan was working as a fellow at Moorfields Eye Hospital until August 2019, then was offered...

The management of chronic central serous chorioretinopathy

1 February 2017 | | Retina / Uvea / Vitreous
Central serous chorioretinopathy (CSCR) is a common retinal disease characterised by one or more serous neurosensory detachments. Patients present with acute onset blurring of vision, metamorphopsia and / or central scotomas. The condition is six times more common in men...

Blind Faith: In Conversation with Mariya Moosajee

16 August 2023 | ONLINE EXCLUSIVE ARTICLES
In light of the BBC releasing Blind Faith: Do genetic eye disease ‘treatments' work? earlier this year, a documentary which follows BBC journalist Ramadan Younes as he investigates practitioners who falsely claim to have ‘treatments’ for genetic eye disease, Eye...

Acute dellen formation post trauma

1 January 2016 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Corneal dellen are saucer-like thinnings, usually of the peripheral cornea [1]. Dellen formation is thought to be related to localised tear film instability [2], specifically the absence of the mucin component of the tear film. Without the mucin layer, dry...

The Leicester Grading System for Foveal Hypoplasia

1 April 2020 | | Ophthalmology, Paediatric Ophthalmology / Strabismus, Neuro-Ophthalmology, Orbit
The University of Leicester Ulverscroft Eye Unit have published the first medical grading system named after the city of Leicester. Infantile nystagmus is characterised by constant and involuntary eye movements and affects 24 per 10,000 people [1]. Onset is usually...

Non-organic visual loss

2 December 2019 | | Ophthalmology, Neuro-Ophthalmology
Patients can present to eye departments with various signs and symptoms (mostly symptoms) with no obvious organic cause. These patients can be labelled with any of a wide range of diagnoses such as functional visual loss, functional overlay, psychosomatic reaction...