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2315 results found

Intensive diabetes therapy and ocular surgery in type 1 diabetes

1 October 2015 | | Retina / Uvea / Vitreous
The Diabetes Control and Complications Trial (DCCT) ran between 1983 and 1993 and showed that intensive glycaemic control was beneficial in reducing diabetic retinopathy in type 1 patients. There was a 76% reduction in onset of retinopathy and a 52%...
Journal of Neuro-Ophthalmology journal cover image

Validity of coding in neuro-ophthalmology within large administrative datasets

7 April 2021 | | Neuro-Ophthalmology
A systematic review of validation studies of the International Classification of Disease (ICD) coding system, ICD-9 and ICD-10 is presented by the authors. Three searches were conducted based on three concepts, firstly health administration claims and ICD codes, secondly diagnostic...
Progress in Retinal and Eye Research journal cover image.

A pulsatile pump in the TM, a new concept in trabecular outflow research

1 October 2021 | | Glaucoma | Aqueous outflow pump, Elastance, Glaucoma, Intraocular pressure regulation, Pulsatile aqueous outflow, Schlemm's canal valves
This is a research article where the authors propose a new model in conceptualising the mechanisms involved in the aqueous outflow at the trabecular meshwork (TM). The authors demonstrated evidence of a pump within the Schlemm’s canal. A pulse generated...

Screening for visual processing deficits in dementia

5 April 2022 | | Neuro-Ophthalmology | Dementia, cognitive impairment, screening test, visual deficits, visuospatial
The Queen Square Screening test for Visual Deficits (QS test) screens for changes in visual processing. It has never been formally validated as a single test. The test consists of a short booklet developed using remnant object and spatial perception...

The rarebit vision test for macular conditions

1 October 2015 | | Retina / Uvea / Vitreous | age-related macular degeneration, macula, macular oedema, rarebit, vision test, visual acuity
Rarebit testing is used to measure low degrees of neuro-visual damage and is available for free on the internet. It consists of a fixed bright light dot presented on a black background. During testing it is presented briefly at different...

Autophagy in lens mitochondria loss

1 April 2014 | | Cataract and Refractive | ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

2018 update on intravitreal injections

1 December 2018 | | Retina / Uvea / Vitreous | Intravitreal injections, Treatment of retinal diseases, Vitreoretinal diseases
In this review article the authors have highlighted the standardised and structured approach to intravitreal injections (IVI) by examining the recent evidence-based literature. IVI is the most commonly performed procedure worldwide with low potential risk of endophthalmitis. IOP spikes are...
Ocular Oncology and Pathology cover image

Quality of life concerns after uveal melanoma diagnosis

5 August 2020 | | Ocular Pathology and Oncology
The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...

Situation analysis of diabetic retinopathy services in eleven countries

1 December 2015 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
A five-year project funded by The Queen Elizabeth Diamond Jubilee Trust is facilitating development of diabetic retinopathy services (DRS) to reduce unnecessary blindness in 10 Commonwealth countries through the establishment of a capacity-building network, the DR-NET part of the Commonwealth...

The Case of Dr Bawa-Garba – Where does the buck stop?

1 August 2018 | | Ophthalmology, Retina / Uvea / Vitreous
The case of Hadiza Bawa-Garba has left all of us in the UK medical profession with an uncomfortable taste in our mouths. We all know that we work under pressure and we will inevitably make mistakes. We all know that...

Innovations in ophthalmology: what can the innovations of the past teach us about tomorrow?

1 June 2014 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
BUOS Prize Essay – 2nd prize winner for 2013 submissions Introduction An essay titled Innovations in Ophthalmology might choose to focus on the history; from cataract couching to femtosecond lasers, ophthalmology has had no shortage of topics worthy of discussion....

Evolving towards an interventional glaucoma mindset

2 February 2024 | | Glaucoma
Traditionally, a newly diagnosed glaucoma patient would be treated first with medical therapy. As the disease progressed or the initial intervention failed to adequately control intraocular pressure (IOP), clinicians would add more drops, selective laser trabeculoplasty (SLT), repeated SLT and...