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Investigating MOG-IgG as a cause for optic perineuritis

Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but in most cases is considered idiopathic. Diagnosis is established by magnetic resonance imaging (MRI) with the demonstration of optic nerve sheath enhancement with sparing of the optic...

A near miss

A 55-year-old gentleman presented with a ‘blurry patch’ to his left eye which he had noticed for the past two months. The visual acuity with correction was 6/5 in the right eye and 6/6 in the left eye on the...

Congenital cranial dysinnervation disorders (CCDDs)

The term congenital cranial dysinnervation disorder (CCDD) was introduced by Gutowski et al. in 2003 to describe strabismus conditions that result from developmental error in innervation of some of the extraocular muscles. Examples of these conditions include Duane’s syndrome and...

25 years of OCT

David Huang first described optical coherence tomography (OCT) in 1991, in his seminal paper on the subject in Science. This method developed the work of others on ophthalmic interferometry, which essentially showed that measuring reflected light could be used to...

Strengthening diabetic retinopathy services in Nigeria through DR-NET – from grass roots to national policy development

This is the third article in a series (see Part 1 and Part 2) reflecting on how shared learning via networks of UK and international eye health professionals is contributing to reducing unnecessary blindness in Nigeria. Earlier articles focused on...

Randomisation, confounding & observational methods in ophthalmic epidemiology

Randomisation and confounding Understanding the relationship between an exposure and an outcome of interest is the central challenge in ophthalmic epidemiology. The exposure may be aetiological, taking the form of a putative risk biological factor, or therapeutic, in the form...

Ophthalmic Aid to Eastern Europe (OAEE)

Peter Cackett, Tim ffytche and Dr Irina Gout reflect on historic ophthalmic aid sent to Eastern Europe. This article was written prior to the horrific events in Ukraine. An appeal for funds and equipment may be made by OAEE later...

Meeting the needs of older patients in optics

Fiona Anderson discusses the important role of community-based eyecare practitioners in meeting the visual needs of ageing patients. It has been well documented that today we live for longer. Statistics show in 1997, around one in every six people (15.9%)...

Acute management of retrobulbar haemorrhage

The authors discuss the importance of rapid diagnosis and correct management of acute RBH presentation to avoid the risk of permanent blindness. Retrobulbar haemorrhage (RBH) is an ocular emergency that occurs due to arterial bleeding in the orbital cavity behind...

Pituitary tumours: why are they so often missed?

Part 2: Clinical varieties, anatomical considerations and case report (see also Part 1 and Part 3) For ophthalmologists there are four types of pituitary tumour to be considered, three of which are named according to the hormone secreted, along with...

Preventing blindness from diabetes: planning a programme of service development and research across Malawi

In sub-Saharan Africa 19.4 million people have diabetes; this is projected to rise to 28.6 million by 2030 [1]. Sight loss from diabetes devastates the lives of working people, affecting the financial stability of the families and communities who depend...

The willingness of patients to participate in an eye donation registry for research

This paper explores the willingness of ophthalmic patients to donate their eyes post-mortem for research purposes. A total of 300 German patients with a median age of 70 years (range 19-95) completed the standardised questionnaire; 45.3% were female and the...