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Questionable ERG use for Vigabatrin screening

The authors aimed to identify the usefulness of electroretinograms (ERGs) as screening for retinal toxicity in patients taking Vigabatrin in a single centre study. This was a retrospective review of full field ERGs and included 170 ERGs of 138 patients...

Nerve head in healthy humans using OCT-angiography

Optical coherence tomography angiography (OCT-A) is a recent, dyeless, and noninvasive imaging technique for evaluating depth-resolved vascular status by capturing the dynamic motion of the erythrocytes. It provides the flow map of major vessels and capillary plexuses separately in different...

Neovascular AMD: fresh recommendations underline standards of best practice

The management of neovascular age-related macular degeneration (nAMD) has advanced dramatically over the past seven years, with the introduction of targeted new therapies that successfully maintain or improve vision in a majority of affected individuals. It’s a fast moving field,...

Second sight: Ian McKinley

I have always been captivated by a true-life story demonstrating the human spirit of triumph over adversity. For me, one of the most memorable sportsmen overcoming an injury has always been the mountaineer Joe Simpson and his tale of survival...

Same day air bubble removal after DSEK/DSAEK

A complete air removal on same day as descemet’s stripping endothelial keratoplasty (DSEK/DSAEK) leads to prompt restoration of the anterior chamber and thus has been hypothesised to assist with the recovery of endothelial function and promote graft adhesion. The results...

What’s Eating Gilbert Pete

“Please phone Mr C Lyon ASAP on 0131 334 9171” This was a message from my secretary waiting for me on my computer one morning shortly after I was appointed a consultant. The name did not ring any bells but...

“I can’t see nothing out of that eye, you ....!”

This is exactly the call you don’t want to receive at 11 at night. The A&E colleague phoned to inform me about a young man who was kicked several times in the face and could not see out of one...

‘The Way Forward’ champions clinicians as architects of patient-centred service redesign

The demographic time bomb poses the dilemma of how more healthcare can be delivered to the UK’s ageing population without commensurate growth in resources. The Way Forward Project provides a robust resource for clinical centres to better identify and implement...

OCT imaging of occluded puncta

This is a description of the use of enhanced depth optical coherence tomography (OCT) to see whether a patent ampulla or canaliculus is detectable in patients with absent or occluded puncta. Nine occluded puncta of six patients with epiphora were...

Treatment options for septic cavernous sinus thrombosis

Septic cavernous sinus thrombosis is a rare but serious complication of infection of the cavernous sinuses. Potential therapies include antibiotics, corticosteroids and anticoagulation, as well as surgical intervention for source control of the infection. The authors report that there is...

Retinal prosthetics: science fiction or a vision for the future?

“Is it a fact – or have I dreamt it – that, by means of electricity, the world of matter has become a great nerve, vibrating thousands of miles in a breathless point of time?” – Nathaniel Hawthorne, The House...

Avoiding investigations through history taking and examinations to differentiate serious from comparably benign aetiology

*Joint first authors. Introduction Anisocoria can be a sign of neurological deficit, necessitating numerous investigations [1]. This case report explores how expensive and time-consuming investigations can be avoided by thorough history taking and examination to differentiate serious from comparably benign...