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What's trending Dec/Jan 2021
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #threeblindmice US company Nanoscope Therapeutics has developed a new treatment which is hoped will restore vision in those affected by retinal...
Analysis and outcome of explanted hydroxyapatite orbital implants
This is a retrospective case series over 11 years of 25 patients with exposed synthetic hydroxyapatite orbital implants who underwent explantation and simultaneous replacement with a dermis fat graft. All patients had signs of infection and had been treated with...Ocular bubbly: a vitreoretinal update on the art of gases
The authors remind us of the revolutionary impact gases have had on retinal surgery. In 1938, Rosengren attempted to improve his retina repair surgical outcomes [1]. He discovered that suturing the retina or pressing externally on the sclera were not...
Ocular manifestations of Whipple’s disease
In this retrospective review of 217 patients with Whipple’s disease (WD), the authors reviewed the presentations of those with ocular manifestations. Ocular signs of WD are under recognised, frequently resulting in misdiagnosis and mismanagement. Mayo Data Explorer, a Mayo Clinic...
Incomplete teprotumumab treatment for thyroid eye disease
This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...
Management of restrictive diplopia after ptergium surgery
This single centre retrospective case series included 15 patients with restrictive diplopia after ptergium excision. The mean time from surgery to diplopia was six months and all patients had a moderate limitation of abduction in the operated eye causing an...
An unusual case of partial oculomotor nerve palsy
The authors present an unusual case of intra-axial oculomotor nerve involvement due to midbrain infarction. The 65-year-old male patient presented with unilateral complete blepharoptosis and slight limitation of upgaze. Neurological examination revealed a complete ptosis of the left eyelid, slight...
RPE tears after intravitreal Lucentis
The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...
Intravitreal bevacizumab vs. ranibizumab in the treatment of macular oedema due to BRVO
This is a randomised, prospective, non-inferiority trial of 75 patients with macular oedema due to a branch retinal vein occlusion (BRVO) who received intravitreal injections of ranibizumab or bevacizumab after 1:1 block randomisation. This study is to measure the difference...Fusarium keratitis in a patient with alcohol dependence
Treatment of fungal keratitis secondary to the Fusarium species remains a challenge. Although relatively more common in warmer climates, this corneal infection is rare in the UK. Most cases have been reported in farmers and are often preceded by trauma....
Is pre-eclampsia / eclampsia a risk factor for non-infective uveitis?
This population based retrospective matched cohort study was the first of its kind to suggest an association between preeclampsia / eclampsia (PEE) and non-infective uveitis (NIU). They used the Longitudinal National Health Insurance database in Taiwan to assess 2073 post-delivery...
