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Incomplete teprotumumab treatment for thyroid eye disease
This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...
Corneal molecular and cellular biology for refractive surgeon
This is an interesting literature review that looks into the recent advances concerning the corneal molecular and cellular processes that are involved in the wound healing response after excimer laser surface ablation and LASIK surgery. It talks about the complex...Bionic eyes: deciphering the neural circuitry of vision restoration
As the boundaries between technology and biology blur, retinal prosthetics, often dubbed ‘bionic eyes’, present a ground-breaking paradigm shift in addressing blindness. This article delves into the captivating scientific intricacies of these neural interfaces, exploring their mechanisms of action, current...Are social media promoting ocular protection in the community?
During the Covid-19 pandemic, many countries worldwide introduced lockdown measures to control infection, causing people to spend more time at home. This resulted in reports of increasing incidences of do-it-yourself (DIY)-related trauma. When the Covid-19 pandemic started in December 2019,...
Fungi in chronic anterior blepharitis
In this prospective, non-randomised cross-sectional study the authors demonstrate the presence of fungi in patients with chronic anterior blepharitis of at least two years duration. Eyelash samples were obtained by epilation with sterile forceps and evaluated with PAS staining, fungal...Effective management of dry eye and ocular surface disease
Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...
PI drops and respiratory change during surgery
Five percent povidone-iodine (PI) topical application to the eye has been observed to cause apnoea under general anaesthetic (GAS). The authors designed a randomised single-blinded controlled trial to evaluate changes in respiration caused by PI eye drops. They recruited 100...Retinal prosthetics: science fiction or a vision for the future?
“Is it a fact – or have I dreamt it – that, by means of electricity, the world of matter has become a great nerve, vibrating thousands of miles in a breathless point of time?” – Nathaniel Hawthorne, The House...
Statins inhibit TGFβ2 mediated fibrotic response in astrocytes
Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...Orbis teams up with the Alcon Foundation and OMEGA to improve eyecare in Zambia
The Orbis Flying Eye Hospital returns to Zambia for a three-week training project in Lusaka coinciding with World Sight Day on October 12.SOS (Simplified Ophthalmic Statistics) Part 4: How to present your statistical analysis
This is the last in this series of short guides which we hope provide some guidance in relation to statistical issues researchers may encounter when conducting research, audit or indeed quality improvement projects. Here we focus on an issue that...
