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Methotrexate and mycophenolate mofetil for non-infectious uveitis
This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...
Medical management and diabetic retinopathy progression
The ACCORD Eye Study was designed to evaluate the benefit of intensive glycaemic control (HbA1c <6.0% vs 7.0-7.9%), intensive systolic blood pressure control (<120mmHg vs. <140mmHg), and combined fenofibrate and simvastatin therapy in the development and progression of diabetic retinopathy....
Short-term effects of intravitreal bevacizumab on the cornea
Bevacizumab has been extensively used to treat macula oedema and neovascularisation of the retina and it has also been useful in the management of corneal neovascular diseases. This prospective study aimed to provide more information on the effect bevacizumab may...
Meibomian gland dropout in patients with dry eyes
In this prospective study 264 patients with symptoms of dry eye were examined with a non-contact meibography system to assess the morphological changes in their meibomian glands. These patients were not previously diagnosed with meibomian gland dysfunction and patients with...
Long-term open angle glaucoma cohort study
This was a study to estimate the development of open angle glaucoma (OAG) in a screened and re-examined elderly group as compared to an unscreened group during the same time period. The participants comprised of 856 individuals born in 1915...
Effect of phacoemulsification on trabeculectomy function
Previous studies have reported cataract surgery post trabeculectomy to be detrimental to IOP control. Conversely, other studies have reported phacoemulsification performed before trabeculectomy as a factor for bleb failure. The objective of this retrospective case control study was to evaluate...
Effect of oxygen levels on binocular summation of dark vision
Previous studies have reported conflicting results on the existence of binocular enhancement of dark vision. This study compares monocular and binocular absolute thresholds of dark adaptation in two different populations (healthy individuals and those with chronic respiratory insufficiency). The study...
Ocular blood flow changes in Behcet disease
This study evaluates ocular blood flow changes in both ocular Behcets disease (BD) and non-ocular BD (with or without thrombotic disease) and compares these findings with a healthy control group. A total of 90 eyes with BD were evaluated with...
A rare case of post-traumatic central retinal artery occlusion
Central retinal artery occlusion is rarely associated with traumatic optic neuropathy, this case report details of one such case. The reported case is of a ten-year-old boy presenting after a fall from height with loss of vision in one eye....
Two case reports of late onset adbucens nerve palsy following carotid-cavernous fistula treatment
This report presents two cases of abducens palsy developing with late onset following endovascular treatment for carotid-cavernous fistula. Following this common and effective treatment for carotid-cavernous fistula, an immediate cranial nerve palsy is a common finding. It usually resolves spontaneously....
Choroidal and macular thickness in nonarteritic anterior ischaemic optic neuropathy
This study evaluates the choroidal and macular thickness in patients with chronic nonarteritic anterior ischaemic optic neuropathy (NA-AION). Two groups of subjects were compared, group one included 20 eyes with chronic NA-AION and group two, 31 healthy control eyes. The...
