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Propranolol treatment of infantile haemangioma
This is a retrospective review of 104 patients treated for infantile haemangioma between January 2009 and July 2012. All patients underwent pretesting either with protocol A (administration of test dose with routine observations) or protocol B (cardiology clinic assessment, including...
Combined ranibizumab and ablative therapy for Coat’s disease
The aim of this study was to observe the efficacy of intravitreal ranibizumab (IVR) combined with laser photocoagulation or cryotherapy, for Coats’ disease. Patients younger than 16 years of age who were diagnosed with Coats’ disease were included in this...
Myopia-protective against diabetic retinopathy
This meta-analysis evaluates the current evidence of the relationship between myopia and diabetic retinopathy (DR) risk. A systematic search was performed up to April 2015. Three models were used to assess the association between myopia and risk of DR: axial...
Corneal molecular and cellular biology for refractive surgeon
This is an interesting literature review that looks into the recent advances concerning the corneal molecular and cellular processes that are involved in the wound healing response after excimer laser surface ablation and LASIK surgery. It talks about the complex...
MicroRNAs in cataract
In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...
Conventional vs. accelerated cross-linking
The Dresden protocol of 3mW/cm2 irradiance for 30 minutes has been extensively studied and has shown advantageous clinical and topographical results. However, this protocol is time-consuming and therefore accelerated CXL using higher irradiance to shorten treatment duration has emerged. The...
Endothelial cell loss using different graft injectors in DMEK
This study aimed to investigate endothelial cell loss between two injector systems in descemet membrane endothelial keratoplasty (DMEK) grafts; a glass injector – modified Jones tube and a plastic injector – closed system IOL injector, the Viscoject 2.2 system. DMEK...
Maintenance therapy for CMV endotheliitis
Cytomegalovirus (CMV) has been associated with corneal endotheliitis, leading to endothelial cell loss and corneal decompensation. CMV corneal endotheliitis recurrence can affect between 5-60% of eyes after cessation of anti-CMV therapy. Each recurrence of endotheliitis has a detrimental effect on...
Outcomes of primary and repeat DSAEKs
Retrospective analysis of results following primary and secondary descemet stripping automated endothelial keratoplasty (DSAEKs), carried out in Villa Serena-Villa Igea Private Hospitals in Italy, showed that primary and secondary DSAEK surgery result in similar visual outcomes, refractive errors and endothelial...
Conjunctivochalasis and aqueous tear deficiency – which one causes symptoms?
This review sought to determine whether conjunctivochalasis (CCh) obliterates the fornix tear reservoir and thus mimics aqueous tear deficiency (ATD). Patients were divided into two groups, with aqueous tear deficiency (CCh +ATD) or without (CCh –ATD), based on results of...
Progression in the Early Manifest Glaucoma Trial
The Early Manifest Glaucoma Trial (EMGT) had previously demonstrated without doubt that intraocular pressure reduction decreased the risk of progression in patients with early glaucoma. In this analysis of 306 eyes over eight years from the EMGT, perimetric and optic...
