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Self refracting – child’s play?

Uncorrected refractive error was the leading cause of vision impairment in the world in 2010. Although refractive error may be safely and effectively corrected with spectacles, lack of well-trained refractionists in settings of limited resources may be a major barrier....

Importance of visual fields for detection of progression in glaucoma

Early detection of progression of glaucoma, and escalating treatment is vital to maintain vision in patients. In this paper from the Early Manifest Glaucoma Trial (EMGT) group they compared the earliest detection of progression in visual fields and monoscopic optic...

What about the children? Cornea cross-linking for children with keratoconus

Keratoconus can behave more aggressively in paediatric than in adult patients. Collagen cross-linking has been shown to slow the progression of keratoconus in adults. This systematic review determined the effectiveness of corneal collagen cross-linking (CXL) in children. For this study,...

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Cataract surgery and long-term risk of glaucoma in PEX

The objective of this study was to compare the development of glaucoma and IOP over an extended time period following cataract surgery in eyes with and without pseudoexfoliation syndrome (PEX), and trying to determine the impact of cataract surgery on...

Retinal blood flow changes in glaucoma

This study examined the changes in retinal blood flow and vessel diameter after IOP reduction in high- and low-pressure glaucoma; exfoliation glaucoma (ExG) and normal-tension glaucoma (NTG). Glaucoma progression is seen at times in eyes despite IOP reduction and changes...

OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema

This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....

Zeiss Forum

The tech column this issue reports on the features and experience of using the Zeiss Forum software. I have overseen the installation, troubleshooting, training and use of the software over the last two years. As both a consultant specialising in...

Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice

Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...

Retinal structural features of CMV retinitis

Confocal adaptive optics (AO) technology has enabled cellular level retinal imaging, including imaging of photoreceptors and blood flow. Adaptive optics scanning laser ophthalmoscopy (AOSLO) is a technology that provides high resolution and high contrast retinal images by correcting ocular aberrations....

Swept-source OCT for measuring peripheral anterior synechiae

The authors report on a cross-sectional study looking at swept-source optical coherence tomography (SS-OCT) for measuring the area and degree of peripheral anterior synechiae (PAS) in patients with angle closure glaucoma. The SS-OCT is commercially available, has a laser wavelength...

Changes in drusen and retinal layer volumes prior to CNV development

This retrospective longitudinal study looked at patients with wet age-related macular degeneration (AMD) in one eye who subsequently developed wet AMD in the fellow eye. The aim was to discover whether drusen characteristics or volumes of retinal layers correlate with...