You searched for "intravitreal"

465 results found

Do patient demographics influence AMD clinic attendance during COVID-19 lockdown?

The authors assess the impact of the COVID-19 pandemic on adherence to scheduled clinic appointments among age-related macular degeneration patients in a clinic in North Wales. The COVID-19 pandemic has significantly affected the population, affecting economic and social wellbeing, whilst...

The role of inflammation in the pathophysiology of DMO

Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

Neovascular AMD: fresh recommendations underline standards of best practice

The management of neovascular age-related macular degeneration (nAMD) has advanced dramatically over the past seven years, with the introduction of targeted new therapies that successfully maintain or improve vision in a majority of affected individuals. It’s a fast moving field,...

What effects do repeated Ozurdex implants have in paediatric uveitis?

The aim of this retrospective study was to assess the anatomical and functional results, as well as complications of repeated Ozurdex intravitreal implants in a paediatric (non-infectious) uveitis cohort. Twenty-two eyes (16 patients) received 35 Ozurdex implants over a six...

Complications of limbal stay sutures

There is limited literature describing complications at the limbal suture site. The authors describe two cases with postoperative complications due to use of intraoperative limbal stay sutures. Each case had strabismus surgery at other centres but with presentation to the...

Vitreoretinal Disease: Diagnosis, Management and Clinical Pearls (second edition)

A comprehensive, well-illustrated and highly informative resource providing excellent descriptions of vitreoretinal diseases, their presentation, diagnosis and management. The 40 chapters are grouped into four sections, namely: the Anatomy and Physiology of the vitreous, retina, choroid and retinal pigment epithelium;...

Risk factors for lens dislocation post cataract surgery

This retrospective cohort study in Korea assessed the risk factors for intraocular lens (IOL) dislocation. They used national data of 2,162,191 patients who had had cataract surgery between 2009 and 2016. They excluded any patient who had an IOL dislocation...

Conservative surgical management of optic disc pit maculopathy

Four cases are presented in this case report that illustrates the option of conservative surgical management for optic disc pit complicated by maculopathy (ODP-M). Four men aged 24-67-years-old with no spontaneous resolution of ODP-M for a minimum of three months,...

OCT prognostic factors in AMD patients with peripapillary choroidal neovascularisation

In this retrospective study the authors aimed to investigate the correlation between optical coherence tomography (OCT) findings and visual acuity outcomes after treatment with intravitreal bevacizumab (IVB) injections for age-related macular degeneration (AMD) patients with peripapillary choroidal neovascularisation (PPCNV). Data...

Effect of cataract surgery on inflammation control and vision in uveitis patients

This retrospective longitudinal study from Moorfields, London, UK compared uveitis recurrence rates and vision loss in 309 eyes of uveitis patients post cataract surgery to 300 control uveitis patients. Cataract is a common complication associated with uveitis and leads to...

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Myopic choroidal neovascularisation

This is a review article summarising the latest myopic CNV (choroidal neovascularisation) literature in the clinical experience and management outcomes for recommendation algorithm. The aetiology of the myopic CNV was discussed by the authors under the heading of the heredo-degenerative...