Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...
The authors sought to determine if the plusoptix would provide an accurate estimation of whether an autistic child had amblyopic risk factors. This retrospective study identified 48 children with autism. Undilated plusoptix was undertaken in 25 children aged less than...
The people of the United Kingdom voted by 52% to 48% to leave the European Union (EU) in June 2016, a referendum decision intended by a slim majority to restore national self-determination and achieve what many believed to be a...
The authors describe a study using a questionnaire to determine how patients use their glaucoma medications to investigate the association between patterns of eye drop prescriptions and medication use. They enrolled 67 Japanese patients who had been prescribed topical anti-glaucoma...
The purpose of this study was to measure postoperative agitation using a standardised scale and evaluate whether it is reduced if given clonidine prior to strabismus surgery as compared to placebo. The scales included the Pediatric Anesthesia Emergence Delirium (PAED)...
A paediatric case report of a hidden eyelid laceration following blunt trauma. Blunt injury to the eyelid can result in a multitude of issues, such as damage to the eyelid margin, lacrimal system and surrounding orbit [1]. These can often...
The role of the optometrist has expanded in recent years as community eye care services have changed. With the limited scope of general ophthalmic services (GOS) regulations in most parts of the UK, the funding to support additional care has...
In a recent discussion with colleagues, someone recognised that many, when asked what they do, say, “I am a doctor”. Rather than “I work as a doctor”. This sense of belonging, pride and duty comes with responsibility. Becoming a surgeon,...
The purpose of this study was to determine whether providing access to instrument-based screening equipment would increase the total number of high quality age-appropriate vision screenings provided to pre-school aged children. SPOT vision screening was placed in paediatric offices at...
This study aimed to determine the efficacy of the Shin-Nippon NVision-K5001 autorefractometer using the open-field refractometry principle in the elimination of accommodation in children. One hundred and fourteen patients aged three to six years were recruited. After excluding ocular pathology...