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Injection of methotrexate into silicone oil-filled eyes for grade C PVR

1 October 2019 | | EYE - Vitreo-Retinal
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...

What’s next in retinal imaging? Faster, deeper and full-on

1 April 2015 | | EYE - Vitreo-Retinal, EYE - Imaging
Fast-evolving technological leaps are opening the way toward clinically useful ocular coherence angiography, generating 3-dimensional microvasculature maps without intravenous dye injection, as well as whole-eye imaging, handheld patient-operated optical coherence tomography (OCT) devices and, for challenging vitreoretinal procedures, integrated intraoperative...

Fluorescein angiography and OCT in myopic CNV

1 December 2014 | | EYE - Vitreo-Retinal
Fluorescein angiography (FA) and spectral-domain optical coherence tomography (OCT) are the most common examinations used in the management of anti-VEGF therapy in choroidal neovascularisation (CNV). In comparison to FA, OCT provides a noninvasive evaluation of the macula. Myopic CNV are...
British Journal of Ophthalmology cover

Features of AMD treatment non-responders

1 October 2019 | | EYE - Vitreo-Retinal
This is a retrospective consecutive case series of 365 eyes with age-related macular degeneration (AMD) who had three monthly intravitreal aflibercept treatments for at least 12 months. Responders were defined as complete resolution of exudation, intraretinal oedema, subretinal fluid, pigment...

Two-year results of a T&E aflibercept regime in caucasian PNV

4 October 2023 | | EYE - Vitreo-Retinal
This a retrospective study examining two-year outcomes of patients with pachychoroid neovasculopathy (PNV) treated with a treat and extend (T&E) regimen of intravitreal aflibercept. The mean age was 63.84 ± 7.92 years with nine males (35%) and 17 females (65%)....

Management of retinal diseases: highlights from the AAO 2019 Retina Subspecialty Day Meeting

2 December 2019 | | EYE - Vitreo-Retinal, EYE - General
The author highlights current debate, opinion and late breaking developments in the management of retinal diseases. The American Academy of Ophthalmology’s 2019 Retina Subspecialty Day Meeting was held on 11-12 October, 2019 in San Francisco, USA. Established and emerging innovative...

DR-NET Workshop – information-sharing for strengthening DR programmes

1 October 2021 | | EYE - Vitreo-Retinal, EYE - General
Contributors: Rosie Brennan, Anshul Chauhan, Mona Duggal, John Ellis, Michael Gichangi, Edwin Grayson, Catherine Jamieson, Ankita Kankaria, Oliver Kemp, Hendra Kusuma, Nanda Matthew, Geeta Menon, Habibah Muhiddin, Tunde Peto, Recivall Salongcay, Frank Sandi, Hazel Shillingford-Ricketts, Bernadetha Shilio, Caroline Styles, Sharon...

Simulated ocular surgery

1 June 2015 | | EYE - Oculoplastic, EYE - Orbit
See also Simulated ocular surgery - strabismus surgery and Simulated ocular surgery: pars plana vitrectomy and scleral buckling surgery This is the first of a series of articles that will have three aims. Firstly, to demonstrate why simulated ocular surgery...

Charity work in Cambodia: Culture, cataracts, and cruelty

3 October 2024 | | EYE - General
Cambodia has one of the lowest numbers of eye specialist doctors per capita in the world, and Bita Manzouri takes us on a journey into the charitable work of the Khmer Sight Foundation who are working to combat this. “Ut...

Feb/Mar 2015 Quiz 1

1 February 2015 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
A 79-year-old male presented to the ophthalmic emergency department with a three week history of left eye pain. He also reported visual deterioration in the left eye over the same period. He suffered from degenerative myopia, with his spectacle prescription...

What’s trending? Dec/Jan 2018

1 December 2017 | | EYE - General
A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #scleratattoo Yes, you read that correctly. Scleral tattoos are a relatively new form of extreme body modification. Oddly enough, ‘sclera...

Deciphering dark retinal patches

3 October 2024 | | EYE - Vitreo-Retinal
We present a case of bilateral extensive dark without pressure (DWP) located outside the retinal vascular arcades in a young female. This retinal finding is benign but, in some instances, darkened retinal patches could be associated with potential sight-threatening conditions....