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OCT-A imaging in Grave’s orbitopathy and orbital decompression

In this case series of 12 patients and 24 orbits, the authors describe the changes in the optic nerve and peripapillary blood vessel density in patients with moderate to severe Grave’s Orbitopathy (GO) undergoing orbital decompression. The patients undergoing orbital...

Congenital aniridia with or without retinal detachment

The authors present the clinical and molecular genetic evaluations performed on a large Iranian pedigree with 26 aniridia affected patients in four generations and some with retinal detachment. Members of the family affected with aniridia were invited to participate after...

Intraocular pressure changes following TOHM washout

This retrospective study between 2008 and 2019 of 110 eyes with primary open angle glaucoma (POAG), 33 eyes with ocular hypertension (OHT) and 43 eyes with uveitic glaucoma (UG) evaluated the changes in intraocular pressure (IOP) following topical ocular hypotensive...

Presenting and diagnostic signs of retinoblastoma

This study revisits the presenting signs of retinoblastoma (RB) in the context of current best practice with respect to diagnosis and assessment of RB. This was a retrospective review of 131 consecutive cases, excluding those with positive family history over...

Practice patterns in managing exogenous endophthalmitis

The authors of this study conducted a global survey of medical institutions regarding management of exogenous endophthalmitis to assess current practice patterns for this sight-threatening emergency. Thirty-six (of 42 institutions) responded and were included in the analysis. Results were as...

Literature review on the use of bupivacaine for strabismus management

The purpose of this study was to examine the overall efficacy of bupivacaine (BPX) when used in isolation for the treatment of strabismus. This was a literature review from 1980 to 2021. The search identified 196 papers of which eight...

Care providers view on how to improve care for paediatric conjunctivitis

The authors present a qualitative study. Purposeful sampling was used to recruit physicians or advanced practitioners for paediatric care in emergency, urgent or primary care settings. Semi-structured interviews were either held in-person or by telephone. All participants recruited commonly encountered...

BT for convergence spasm

The aim of this study was to analyse the response of a cohort of patients with convergence spasm to the injection of botulinum toxin (BT) in the medial rectus muscle. This was a retrospective study of six patients with a...

Two illustrative cases of AZOOR

The authors present two illustrative cases of acute zonal occult outer retinopathy (AZOOR) which causes acute idiopathic blind spot enlargement. The disease is characterised by sudden loss of outer retinal function associated with photopsia, with minimal or no fundoscopic changes...

Hormonal contraceptives and IIH

This multicentre retrospective population based case control study investigated whether there was a higher incidence of idiopathic intracranial hypertension (IIH) in those patients taking oral contraceptive pills (OCP) and other hormonal contraceptives. Fifty-three women were diagnosed with IIH between Jan...

Cataract surgery in uveitis

This is a multicentre study of eight UK independent sites of patients with uveitis, undergoing cataract surgery between January 2010 and December 2014. A total of 1173 eyes were compared with a control reference group of 95,573 eyes from the...

Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma

The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...