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Complement Factor H and Factor H-Like protein are expressed in human RPE cells

The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...

A pulsatile pump in the TM, a new concept in trabecular outflow research

This is a research article where the authors propose a new model in conceptualising the mechanisms involved in the aqueous outflow at the trabecular meshwork (TM). The authors demonstrated evidence of a pump within the Schlemm’s canal. A pulse generated...

UKPGS (UK Paediatric Glaucoma Society) Meeting 2023

by SP Gurney The UK Paediatric Glaucoma Society (UKPGS) 2023 annual meeting took place on 27 January at the Cavendish Conference Centre in London. Professor Sir Peng Khaw, UKPGS President, welcomed nearly 100 delegates from around the world, with representation...

Problems in Periorbital Surgery: A Repair Manual

This is a multi-author textbook directed at oculoplastic and plastic surgeons carrying out and managing aesthetic eyelid surgery. The authors are well-known and commonly cite their mentor, Clinton (“Sonny”) McCord as the main inspiration behind the textbook. Each section contains...

The screening and treatment of retinopathy of prematurity

A male child is born at 31 weeks and requires 100% oxygen supplementation with intensive care. What would be the ophthalmic management of this child? In the first instance, it will be useful to know the screening criteria and protocol....

Developments in Ophthalmology: Ophthalmic Radiation Therapy Techniques and Applications

Radiation was discovered by Wilhelm Roentgen in 1895, and since then has been used to treat a variety of cancers. Its therapeutic properties have been widely used for ocular and periocular tumours and inflammatory disease, but the present era is...

Lateral tarsal strip versus Bick’s procedure in correction of eyelid malposition

The authors report a retrospective case series of patients, to evaluate the effectiveness of Lateral Tarsal Strip (LTS) and Bick’s procedure (lateral wedge resection) for all types of involutional lower eyelid malposition, at two centres between January 2012 and 2015....

The value of hospital placements in ophthalmology in general practice specialty training

Pratik Bikkannavar provides insights into the potential benefits a placement in ophthalmology provides General Practice Specialty Trainees (GPSTs) and its valuable purpose for the wider ophthalmic community. Ophthalmic complaints are known to account for up to 1 in every 20...

How do blind and vision impaired people experience loneliness and isolation?

This week Fight for Sight / Vision Foundation released a report highlighting the acute experiences of loneliness among people who are blind or vision impaired.

Corneal dystrophies simplified

Based on biomicroscopic and histopathologic features, corneal dystrophies can be broadly classified into epithelial, Bowman’s layer / anterior stromal, stromal, and endothelial dystrophies. Corneal dystrophies are a group of inherited, bilateral, gradually progressing, non- inflammatory conditions caused by accumulation of...

How to get the most out of your medical school ophthalmology placement

Ophthalmology has become a very popular speciality, generating a vast interest amongst medical students with competition for training posts increasing yearly. Yet it is often difficult to get adequate exposure to the speciality prior to applications, with very limited time...

The future of multi-professional working in eye care

How the integration of service improvement technology, and health promotion will allow eye care professionals to overcome current and future challenges. The future of eye care in the UK is at a precipice. Hospital attendances are increasing year on year,...