You searched for "ophthalmology"

2564 results found

Rituximab as an immunosuppression treatment for thyroid eye disease

Thyroid eye disease is traditionally treated with high dose glucocorticosteroids and surgical orbital decompression, where responses are often inadequate. This medical treatment is centred around symptom control and reduction of thyroid hormone synthesis, not immunosuppression. Rituximab is an anti-CD20 monoclonal...

Selection of visual field test for detection of pituitary disease

This prospective cross-sectional diagnostic accuracy study compared Octopus semi-automated kinetic perimetry (SKP) and Humphrey static automated central perimetry for detection of neurological visual field loss in patients with pituitary disease. Humphrey central 30-2 SITA threshold programme results were compared with...

Visual outcomes, visual fields and optical coherence tomography in paediatric craniopharyngioma

This study reviews the visual outcomes of ten patients under the age of 18 years with craniopharyngioma. The paper also reviews the correlation between visual field (VF) testing and optical coherence tomography (OCT) examination and evaluates the role of OCT...

Silicone rod for ptosis surgery

The authors report their results and complications associated with the use of silicone rod for frontalis suspension lid surgery. This was a retrospective study of 38 eyes (25 patients) with six months follow-up. The group included 19 males and six...

Monocular eye closure following treatment of intermittent exotropia

The purpose of this study was to evaluate the short- and long-term status of monocular eye closure after surgical treatment of intermittent exotropia and to determine whether the status at short-term postoperative follow-up duration remains or can change after long-term...

The impact of conjunctivochalasis on dry eye symptoms and signs

The study aimed to draw a relationship between conjunctivochalasis and dry eye symptoms via a dry eye questionnaire (DEQ5), as well as signs such as tear osmolarity, tear break up time, corneal staining, Schirmer score, meibomian gland dropout, eye lid...

Sustained elevation of extracellular ATP in chronic glaucoma

Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...

Postural control in glaucoma patients with virtual reality

The authors report on a cross-sectional study evaluating postural control and history of falls in glaucoma patients. History of falls was obtained using the Falls Screening and Referral Algorithm. Postural stability was assessed using a force platform under four conditions:...

A case series of acquired esotropia in cerebellar disease

Acquired esotropia in cerebellar disease is well described but under-recognised. The pathogenesis of cerebellar esotropia is controversial. It is suggested it may be a result of disruption to central vestibular pathways. This article reports a case series of seven adults...

Literature review of isolated ocular motor nerve palsies

Patients aged over 50 presenting with isolated nerve palsies of the third (pupil sparring), fourth or sixth nerves, are often described as having microvascular extraocular palsies. This review looks critically at the evidence surrounding these microvascular non-arteritic extraocular palsies and...

Surgical outcomes in third nerve palsy

The authors of this article explore the factors associated with successful surgical outcomes in third nerve palsy, which is known to be difficult to treat. A number of case notes were reviewed for patients who underwent surgery or botulinum toxin...

Structural effects of migraine on the retina

Migraine is a common, chronic, multifactorial neuro-vascular disorder typically characterised by recurrent attacks of disabling headache and autonomic nervous system dysfunction (migraine without aura). Up to one third of patients also have neurological aura symptoms (migraine with aura). The objective...