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Squamous metaplasia of conjunctival epithelial cells with soft contact lens wear versus non-lens wearers

Conjunctiva is composed of non-squamous epithelial cells interspersed with goblet cells, which is a secretory epithelium. Squamous metaplasia is a transformation to non-secretory epithelium, ‘keratinised’ and enlargement of the conjunctival non-goblet cells and relatively shrunken nuclei are seen on impression...

Local campaigner with glaucoma from Manchester shortlisted for RNIB See Differently Award

A man from Manchester has been shortlisted for an RNIB See Differently Award in recognition of his campaigning to raise awareness of glaucoma and the importance of eye care among young people and those of East Asian heritage.

WATCH: Beyond 2020 with the Andean Medical Mission

This Andean Medical Mission series is called Beyond 2020, and focuses on the many aspects of creating services which will ultimately impact on eliminating avoidable blindness in countries with developing eyecare services.

WATCH: Beyond 2020 with the Andean Medical Mission

This Andean Medical Mission series is called Beyond 2020, and focuses on the many aspects of creating services which will ultimately impact on eliminating avoidable blindness in countries with developing eyecare services.

Randomisation, confounding & observational methods in ophthalmic epidemiology

Randomisation and confounding Understanding the relationship between an exposure and an outcome of interest is the central challenge in ophthalmic epidemiology. The exposure may be aetiological, taking the form of a putative risk biological factor, or therapeutic, in the form...

Medical malpractice in uveitis: a review of clinical entities and outcomes

This paper presents a retrospective review of malpractice verdicts, rulings and settlements in the United States. Twenty-five cases of uveitis-related litigation spanning 1971-2014 were identified from the database representing 2.3% of all cases. Forty-eight percent of the cases were infectious....

A case report of alternating anisocoria with associated nasal congestion

The authors have described a group of healthy individuals who show alternating anisocoria, in a previous paper. In these cases, the pupil asymmetry alternates between eyes every few hours, with no observed instances when both pupils are equal in size....

Does cornea cross-linkage reduce the rate of corneal transplants in keratoconus?

Cornea cross-linking (CXL) is a relatively new treatment in the management of keratoconus, which may help prevent the need for corneal transplant. This paper investigates if the introduction of corneal cross-linkage has reduced the number of corneal transplants performed annually...

Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

Diagnostic procedures in vitreoretinal lymphoma.

This paper presented a retrospective review of medical records of HIV negative immunocompetent patients diagnosed with vitreoretinal lymphoma between 1994 and 2012. The aim of the paper was to evaluate the type and number of diagnostic interventions required to confirm...

RPE use similar pathway to regulatory T cells to inhibit immune response

Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....