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Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

ESASO Course Series Vol. 4 Optical Coherence Tomography

This book, which is the latest volume from the European School for Advanced Studies in Ophthalmology (ESASO) course series, is a revelation and joy to review. This compact volume provides an introduction and an update to the most recent technological...

Intraocular Inflammation

Intraocular Inflammation is an encyclopedic treatise on uveitis. The editors have invited several experts in the field to author different chapters and provide the reader with an excellent repository of knowledge, experience and evidence on the subject. The approach to...

Vitreoretinal Disease: Diagnosis, Management and Clinical Pearls (second edition)

A comprehensive, well-illustrated and highly informative resource providing excellent descriptions of vitreoretinal diseases, their presentation, diagnosis and management. The 40 chapters are grouped into four sections, namely: the Anatomy and Physiology of the vitreous, retina, choroid and retinal pigment epithelium;...

The Duke Elder Exam of Ophthalmology: A Comprehensive Guide for Success

The Duke Elder Exam is an annual competitive national undergraduate exam organised by the Royal College of Ophthalmologists. This two-hour exam consists of 90 multiple-choice questions (MCQs) and examines clinical ophthalmology, ocular physiology, anatomy, pathology, genetics and socio-economic medicine related...

300 MCQs for the Duke Elder Ophthalmology Exam

The Duke Elder undergraduate prize examination is held by the Royal College of Ophthalmologists annually for undergraduate medical students. It is a competitive examination covering clinical ophthalmology as well as the ocular basic sciences, optics, statistics and socio-economic medicine. For...

Keratolimbal allograft and tumour transmission

This case report describes tumour transmission from keratolimbal allograft donor to recipient. A 68-year-old woman underwent keratolimbal allograft (KLAL) for limbal stem cell failure from a donor, who died of invasive breast carcinoma that had metastasised to multiple levels of...

Late stromal rejection in DALK

This case series reported on late stromal rejections in eyes after uncomplicated deep anterior lamellar keratoplasties (DALKs). Four eyes of three patients experienced episodes of isolated stromal rejection 33 to 46 months after surgically uncomplicated DALKs and a minimum of...

Rituximab efficacy for juvenile idiopathic arthritis

This is a retrospective study about the long-term efficacy of rituximab in patients with severe juvenile idiopathic arthritis (JIA)-associated uveitis. A total of eight patients (15 eyes) were recruited in this study in a single tertiary referral centre from Italy....

Retinal structural features of CMV retinitis

Confocal adaptive optics (AO) technology has enabled cellular level retinal imaging, including imaging of photoreceptors and blood flow. Adaptive optics scanning laser ophthalmoscopy (AOSLO) is a technology that provides high resolution and high contrast retinal images by correcting ocular aberrations....

Mast cells in Graves’ ophthalmopathy

Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...

Hereditary profile of retinal detachment

This review sought to clarify some of the heritable elements of rhegmatogenous retinal detachment (RRD). The familial element of RRD is well established, with the sibling recurrence risk ratio being 2.1 (Mitry and colleagues), and the parent-offspring recurrence risk ratio...