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Broadening of treatment options for potentially blinding retinal conditions

Rod McNeil provides an update on a promising bispecific antibody recently approved for treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO) and considers emerging developments in biosimilars to established anti-vascular endothelial growth factor (anti-VEGF) therapies, including...

The writer: publishing my first book as a trainee

Medicine is very hierarchical. Indeed, Hippocrates himself laid the foundation of the apprenticeship that is medical training and while it is the noble duty of the boss to pass on information and ask for tasks to be undertaken as a...

Retinal Pharmacotherapeutics (Developments in Ophthalmology)

Retinal Pharmacotherapeutics is volume 55 in the ‘Developments in Ophthalmology’ series released by Karger. As the name of the series suggests it aims to explore current and future developments in retinal therapeutics. The book itself is split into six main...

Infantile vertical nystagmus

The authors describe the clinical characteristics and long-term outcomes of infants who presented with isolated vertical nystagmus in infancy, age-appropriate visual behaviours and unremarkable neuroimaging studies. The study included eight patients presenting at <1-year-old. All had age-appropriate behaviour. At presentation...

Cystoid macular oedema following cataract surgery

This review covers the history, incidence, diagnosis, risk factors, pathophysiology and medical management of postoperative macular oedema (PCMO), with a particular emphasis on key contemporary studies and novel observations. The authors revisit the incidence of well-established risk factors including intraoperative...

Laser pointer maculopathy

The objective of this study was to describe the potential clinical presentations of retinal pathology resulting from exposure to laser pointers. The study included eight eyes of seven patients. Mean age was 18.7 years (12-36). Most were accidental self-inflicted while...

Features of AMD treatment non-responders

This is a retrospective consecutive case series of 365 eyes with age-related macular degeneration (AMD) who had three monthly intravitreal aflibercept treatments for at least 12 months. Responders were defined as complete resolution of exudation, intraretinal oedema, subretinal fluid, pigment...

Timed resolution of subperiosteal empyema

The purpose of this study was to examine the quantitative changes in subperiosteal empyema (SE) size over time and the time to complete radiographic resolution of this. This was a retrospective case review of 15 cases with orbital cellulitis and...

Using MRI to assess normal variation in optic chiasm anatomy

The authors present an MRI study including 61 MRI scans using a 1.5 T with slice thickness of 1 or 5mm and the sequence showing the highest resolution of the chiasm. A predetermined set of measurements were taken in a...

How a paediatric population presented with diplopia

The authors present the results of a retrospective records review of 244 children presenting with diplopia over a three-year period. The majority of cases presented to paediatric ophthalmology clinic; other routes of presentation included eye casualty, neuro-ophthalmology or another eye...

A novel approach to suprachoroidal haemorrhage drainage

The authors describe a novel surgical technique for external drainage of choroidal detachment / suprachoroidal haemorrhage with a butterfly needle. Six eyes with serous and / or haemorrhagic choroidal detachments (five from complicated cataract surgery with vitreous loss, one globe...

Evaluation of fluocinolone acetonide in the management of BRC

This is a single-centre, retrospective, intervention study of 15 eyes of birdshot retinochoroiditis (BRC) patients who received Iluvein, with a mean follow-up period of 31 months. Five eyes had previously received dexamethasone intravitreal implant 0.7mg (Ozurdex). Fluorescein angiography (FA) showed...