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2548 results found

Meta-analysis of HLA B27 associated acute anterior uveitis

A literature-based meta-analysis was carried out to look at the various clinical features associated with HLA- B27 acute anterior uveitis (AAU). After an extensive search of literature for HLA B27 uveitis was conducted, 735 results were obtained. Twenty-nine articles were...

Systemic pharmacology of intravitreal anti-VEGF

This study aimed to evaluate and compare serum drug concentrations and plasma free-VEGF concentrations in patients with AMD, DME, or RVO receiving intravitreal injections of aflibercept, bevacizumab or ranibizumab. This prospective study enrolled patients from several offices of a single...

AOP calls for ‘bold thinking’ in response to DHSC request for new minor and urgent eyecare service

The development of a standard specification for ICBs is welcome but ambition for a national approach ‘should not be sacrificed’.

How common are ocular motor cranial nerve palsies following TBI?

This retrospective cohort study aimed to report the incidence of ocular cranial nerve palsy as a result of traumatic brain injury (TBI). Patients were identified using an insurance database using codes from the International Classification of Disease 9th and 10th...

Oral azithromycin for meibomian gland disease

Oral tetracyclines have been the traditional systemic treatment of blepharitis and acne rosacea, through inhibiting bacterial lipase production and reducing fatty acids. However, tetracyclines have a number of adverse side-effects and are required to be taken for a long duration...

Penetrating keratoplasties in infants

This retrospective review looked at endothelial cell counts (ECC) following penetrating keratoplasties (PKP) performed in infants within the first year of their life. One hundred eyes of 71 patients had their first PKP during the study period (1998-2013). In 30%...

Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes

This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...

Investigation into the anatomical differences of eyelashes between Caucasian and Indian specimens

This study investigated the anatomy of human eyelashes through analysis of root depth, angle, and spatial relationship. Four eyelids from Caucasian donors were obtained from fresh donors and four eyelids from Indian donors were obtained from eye bank calls. The...

How common is ocular trauma in children and what are the clinical features?

The authors present a multicenter retrospective case review with the aim of reporting the incidence and characteristics of paediatric ocular trauma. Records for individuals aged 18 and under with a diagnosis of globe, orbit or adnexal injury over a 10-year...

Squamous metaplasia of conjunctival epithelial cells with soft contact lens wear versus non-lens wearers

Conjunctiva is composed of non-squamous epithelial cells interspersed with goblet cells, which is a secretory epithelium. Squamous metaplasia is a transformation to non-secretory epithelium, ‘keratinised’ and enlargement of the conjunctival non-goblet cells and relatively shrunken nuclei are seen on impression...

Uveitis in HIV infected persons

Before the advent of highly active antiretroviral therapy (HAART), uveitis, in particular cytomegalovirus (CMV) retinitis, was the most common cause of visual loss in patients with AIDS. HAART has altered the cause of ocular disease in HIV infected individuals by...

RAPD in glaucoma screening

A study was conducted to investigate the relative afferent pupillary defect (RAPD) by swinging flashlight as a potentially useful screening test for glaucomatous optic neuropathy. The authors recruited 107 subjects with or without glaucoma from a clinic population. A medical...