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Insights in resistant diabetic macular oedema

5 August 2022 | | Retina / Uvea / Vitreous
This article gives a bird’s eye review of the different modalities for the treatment of diabetic macular oedema (DME). The debut of anti-VEGFs has brought a paradigm shift in DME management. This treatment has now become a major breakthrough in...

DRIL after macular oedema treatment in BRVO

1 June 2019 | | Retina / Uvea / Vitreous | Anti-vascular endothelial growth factor treatment, Branch retinal vein occlusion, Disorganization of the retinal inner layer, Spectral-domain optical coherence tomography, Visual acuity
The authors report the analysis of a single-site, retrospective, cross-sectional study to evaluate the association between disorganisation of the retinal inner layers (DRIL) and visual acuity (VA) after anti-VEGF treatment for macular oedema (MO) due to branch retinal vein occlusion...

RPE tears after intravitreal Lucentis

1 February 2017 | | Retina / Uvea / Vitreous
The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...

5-FU vs. Avastin as adjunct to conjunctival autograft

1 October 2016 | | Cornea / External Eye Disease
The authors compare the outcome of pterygium treatment using 5-fluorouracil as an adjunct to free conjunctival autograft versus bevacizumab (Avastin) as an adjunct to free conjunctival autograft, via a randomised controlled prospective study. Seventy eyes of 70 patients were included...

Intravitreal bevacizumab vs. ranibizumab in the treatment of macular oedema due to BRVO

1 June 2016 | | Paediatric Ophthalmology / Strabismus | Macula, Retina
This is a randomised, prospective, non-inferiority trial of 75 patients with macular oedema due to a branch retinal vein occlusion (BRVO) who received intravitreal injections of ranibizumab or bevacizumab after 1:1 block randomisation. This study is to measure the difference...

The disease burden of AMD

1 December 2015 | | Retina / Uvea / Vitreous
In this multi-centre, prospective, observational, time and motion study the authors assessed the time burden of managing wet AMD for doctors, staff, patients and caregivers in the USA. The study spanned the period from March 2011 to August 2012, and...

How does cataract surgery affect eyes with wet AMD?

1 October 2015 | | Cataract and Refractive
In this retrospective cohort study the authors’ primary objective was to assess whether cataract surgery in eyes with wet age-related macular degeneration (AMD), triggered its progression. The surgical group comprised of 40 eyes versus 42 eyes in the non-surgical control...

Clinical evaluation of a multifocal aspheric diffractive intraocular lens

1 February 2014 | | Cataract and Refractive | Lens and zonules, Optics and Refraction, Treatment Surgery
This is a multi-centre prospective study involving five different centres in Europe including 52 patients with cataract. The average age was 68.5±10.5 years, 35 females were bilateral implanted with aspheric diffractive multifocal lens implantation of the Tecnis 1-Piece multifocal intraocular...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

3 February 2023 | | Ophthalmology
Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

A brief history of colour vision

1 April 2019 | | Ophthalmology, Optometry
Andrew Want takes a look at how colour vision has evolved in humans and animals and how it differs across species. Colour vision is something that we often take for granted, but it has become so intrinsic to the way...

Working smarter not harder: How to transform eyecare delivery in the United Kingdom (part 1)

1 December 2021 | | Ophthalmology, Optometry
Are we doing enough to meet the current demands on ophthalmic services? In part one of a two-part series (see Part 2 here), Rosalind Harrison takes a look at how efficiency has been improved in eyecare services in the US....

A single intravitreal bevacizumab in the treatment of breast carcinoma related choroidal metastasis

1 June 2015 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Case report Choroidal metastasis represents a common form of intraocular malignancies occurring in up to 10% of patients with systemic metastasis [1]. The most common primary sites of ocular metastasis are breast carcinoma in women and lung carcinoma in men,...