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Cyclosporine A and pterygium fibroblasts

The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...

Comparison of methods of central corneal thickness measurement in glaucoma

This prospective study was done to compare the accuracy and reproducibility of central corneal thickness measured by hand-held and disc-mounted ultrasound pachymeter in glaucoma patients. Sixty-five patients were included in the study. Patients with corneal diseases, corneal astigmatism >3 diopters...

Rituximab as an immunosuppression treatment for thyroid eye disease

Thyroid eye disease is traditionally treated with high dose glucocorticosteroids and surgical orbital decompression, where responses are often inadequate. This medical treatment is centred around symptom control and reduction of thyroid hormone synthesis, not immunosuppression. Rituximab is an anti-CD20 monoclonal...

Selection of visual field test for detection of pituitary disease

This prospective cross-sectional diagnostic accuracy study compared Octopus semi-automated kinetic perimetry (SKP) and Humphrey static automated central perimetry for detection of neurological visual field loss in patients with pituitary disease. Humphrey central 30-2 SITA threshold programme results were compared with...

Association between neuro-ophthalmology signs and chronic ataxia in children

Neuro-ophthalmological signs (N-OS) occur commonly in children with chronic ataxia. This study describes the N-OS and their frequencies, in general and by specific disease aetiology in paediatric patients with chronic ataxia. In total, 184 patients under the age of 17...

Visual outcomes, visual fields and optical coherence tomography in paediatric craniopharyngioma

This study reviews the visual outcomes of ten patients under the age of 18 years with craniopharyngioma. The paper also reviews the correlation between visual field (VF) testing and optical coherence tomography (OCT) examination and evaluates the role of OCT...

Meibomian gland alteration in patients with primary chronic dacryocystitis: An in vivo confocal microscopy study

Chronic dacryocystitis affects tear film functionality and can predispose to ocular surface disease, however the specific effect of chronic dacryocystitis on meibomian gland function has not been studied. This group therefore performed in vivo confocal microscopy in 28 patients’ eyes...

Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience

Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...

Lower postoperative scar height is associated with increased postoperative trichiasis one year after bilamellar tarsal rotation surgery

Bilamellar tarsal rotation has been a key component of the WHO SAFE approach to blindness from trichiaisis (surgery, antibiotics, facial hygiene, environment). The World Health Organisation (WHO) manual describes the procedure as a full thickness blepharotomy placed 3.0mm above and...

Ointment related granulomas post-blepharoplasty

This is a retrospective review of eight patients who developed granulomatous masses after lower lid blepharoplasty. All patients had sutureless bilateral trans-conjunctival surgery, and lubricating ointment was instilled into the inferior fornix postoperatively for two days. Painless lower lid masses...

Evaluating ocular motor functions

Traditionally orthoptists are specialised in assessing ocular motor disorders. This article introduces the ocular motor score as a new clinical tool for screening and follow-up for children and young adults. The protocol consists of 15 tests such as stereoacuity, strabismus,...

Silicone rod for ptosis surgery

The authors report their results and complications associated with the use of silicone rod for frontalis suspension lid surgery. This was a retrospective study of 38 eyes (25 patients) with six months follow-up. The group included 19 males and six...