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Efficacy and safety of intravitreal aflibercept injection in wet age-related macular degeneration

This is a sub-group study of double masked review of patients randomised to different dosages and treatment frequency compared between aflibercept and ranibizumab treatment. This is to evaluate the efficacy and safety of intravitreal aflibercept (IVT-AFL) in Japanese patients with...

Is there an association between dry eye disease and depression and anxiety?

Dry eye disease is a widespread ocular surface condition (prevalence 5.5-33.7%) that has been previously linked to systemic diseases, such as Sjogren, rheumatoid arthritis and more recently possibly also depression, in small population-based studies. The authors’ aim was to investigate...

Visual performance of new multifocal IOL

Multifocal IOLs (MIOLs) keep evolving to try and get the best outcome in terms of vision and reduction of side-effects. This prospective interventional study was carried out on 34 eyes of 17 patients (11 women (65%) and six men (35%))...

Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis

In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...

Injection frequency and anatomic outcomes following conversion to Aflibercept in neovascular AMD patients

This is a retrospective study of patients with neovascular age-related macular degeneration (AMD) treated with intravitreal Lucentis and / or Avastin who were switched to aflibercept (Eylea). This study was carried out by the Casey Eye Institute retinal clinics, between...

Intraoperative floppy iris syndrome and prevalence of intraoperative complications

Alpha-blockers (particularly of the selective type) are known to be associated with intraoperative floppy iris (IFIS) and poor dilation, which can present in various severities during cataract surgery and need to be recognised in order to avoid intraoperative complications. Methods...

Anterior and posterior capsular opacification with the Tecnis ZCBOO and AcrySof SA60AT IOL

This a randomised, controlled, prospective and double-blind study comparing the anterior capsular opacification (ACO) and posterior capsular opacification (PCO) outcomes with two types of single-piece hydrophobic acrylic intraocular lenses (IOL), and AcrySof SA60AT – Group A, and Tecnis ZCBOO –...

Epiretinal membranes in uveitic macular oedema

Epiretinal membrane (ERM) formation in uveitic macular oedema is a fairly common structural complication of the retina. The authors describe a retrospective case series of 104 eyes of 77 patients with uveitic macular oedema from a tertiary centre. The treatment...

Clinical evaluation of a multifocal aspheric diffractive intraocular lens

This is a multi-centre prospective study involving five different centres in Europe including 52 patients with cataract. The average age was 68.5±10.5 years, 35 females were bilateral implanted with aspheric diffractive multifocal lens implantation of the Tecnis 1-Piece multifocal intraocular...

Comparison of bilateral lateral and unilateral recession resection for IXT

This is a retrospective review study of patients between the ages of three and 15 years old with the basic type of intermittent exotropia (IXT) who had strabismus surgery between January 2003 to September 2009. There were 85 patients included...

Comparison of visual field indices between normal adults and children

The authors present a prospective observational study which aimed to compare visual field indices with retinal nerve fibre layer (RNFL) thickness using optical coherence tomography (OCT) in normal adults and children. Children aged 6–18 years were recruited from a single...