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Ocular manifestations of multiple sclerosis: an overview

1 December 2022 | | Ophthalmology, Genetics
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

Streamlining cataract lists: how are you managing it?

1 October 2021 | | Ophthalmology, Cataract and Refractive
Mr Jonathan Ross, in conversation with Ms Bita Manzouri, provides a personal perspective on challenges and opportunities shaping the future of cataract surgery services across the hospital eye service. Redesigning cataract pathways in response to COVID-19 Bita Manzouri: Over the...

Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management

1 December 2016 | | Retina / Uvea / Vitreous
Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...

Optical coherence tomography – reinventing the eye examination

1 October 2016 | | Retina / Uvea / Vitreous, Imaging
It has been 25 years since Huang et al. presented the first optical coherence tomography (OCT) images in Science [1]. With vast improvements in OCT technology over the years, it is now possible to acquire high-resolution cross-sectional images of the...

Simulated ocular surgery

1 June 2015 | | Oculoplastics, Orbit
See also Simulated ocular surgery - strabismus surgery and Simulated ocular surgery: pars plana vitrectomy and scleral buckling surgery This is the first of a series of articles that will have three aims. Firstly, to demonstrate why simulated ocular surgery...

Macular holes: A brief review

1 August 2017 | | Retina / Uvea / Vitreous
The classification of macular holes has been modernised by OCT findings. This is a brief review and encompasses the historical literature on macular holes. A macular hole is an anatomical discontinuation of the neurosensory retina at the centre of the...

Proning and the pandemic - ocular complications seen in critical care

6 April 2021 | | Ophthalmology, Retina / Uvea / Vitreous, Orbit, Cornea / External Eye Disease
Priyanka Sanghi and her co-authors explore the ocular complications seen in critical care units throughout the country as we treat patients through this challenging time. The SARS-Cov-2 (COVID-19) pandemic has placed the NHS and critical care services under immense strain,...

Corneal dystrophies simplified

1 February 2017 | | Cornea / External Eye Disease
Based on biomicroscopic and histopathologic features, corneal dystrophies can be broadly classified into epithelial, Bowman’s layer / anterior stromal, stromal, and endothelial dystrophies. Corneal dystrophies are a group of inherited, bilateral, gradually progressing, non- inflammatory conditions caused by accumulation of...

Retinal prosthetics: science fiction or a vision for the future?

2 December 2019 | | Retina / Uvea / Vitreous, Ophthalmology
“Is it a fact – or have I dreamt it – that, by means of electricity, the world of matter has become a great nerve, vibrating thousands of miles in a breathless point of time?” – Nathaniel Hawthorne, The House...

Developments in oculoplastic surgery

1 June 2018 | | Oculoplastics
A study of NHS practice demonstrated significant patient-reported quality-of-life improvements from commonly performed oculoplastic operations: entropion repair, ectropion repair, ptosis repair and dacrocystorhinostomy (DCR) [1]. In recent years, surgical and non-surgical approaches to functional and aesthetic oculoplastic surgery have advanced...

Optic nerve swelling – your survival guide (part 1)

1 August 2017 | | Neuro-Ophthalmology
Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...

The International AMD Genomics Consortium study: another success in understanding the complex genetics of AMD

1 April 2017 | | Genetics
Age-related macular degeneration (AMD) is a neurodegenerative complex disease of the eye and a major cause of blindness and visual impairment among the elderly worldwide. The early stages of the disease are characterised by asymptomatic pigmentary abnormalities and accumulation of...