You searched for "choroid"
Nicotine accelerates diabetes induced retinal changes
1 June 2015
| Khadijah Basheer
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EYE - Vitreo-Retinal
This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...
Ocular manifestations of multiple sclerosis: an overview
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...Radiation retinopathy
The authors review the current treatment options for this condition. Radiation retinopathy (RR) occurs as a complication after exposure to any type of radiation (external beam, plaque brachytherapy and stereotactic radiosurgery) in the orbital or adnexal region. These include nasopharyngeal...Accommodation in children
1 June 2018
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
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Accommodation, children, reading, targets, text size
The purpose of this pilot study was to establish typical accommodative responses at 1/3m in children to targets of varying complexity and visual / cognitive demand. This was a study of 18 children aged six to seven years and six...
Needling procedure for failed bleb
5 April 2022
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
The aim of this study was to determine the efficacy of needling with 5-FU after failed filtering procedures in the paediatric population. This was a retrospective review of 324 filtration surgeries in 265 children with 55 eyes (16.9%) undergoing needling...
Finasteride and central serous chorioretinopathy
1 June 2017
| Sofia Rokerya
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EYE - Vitreo-Retinal
The pathophysiology of central serous chorioretinopathy (CSC) is complex and has not been fully elucidated. Suggested theories include hyperpermeability and increased hydrostatic pressure in the choroidal vasculature, which creates RPE detachments overwhelming the RPE barrier function, leading to accumulation of...
Understanding spaceflight-associated neuro-ocular syndrome (SANS): what do we know?
Introduction Formerly known as visual impairment and intracranial pressure syndrome (VIIP), space-related neuro-ocular syndrome (SANS) is defined by a collection of ophthalmic and neurological findings in astronauts after long-term spaceflight [1]. Changes in the eyeball, such as hyperopic shift, during...A review of neuro and retinal imaging findings in Alzheimer’s disease
6 February 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a systematic review with the aim of assessing the relationship between retinal and cerebral changes in Alzheimer’s disease (AD), mild cognitive impairment and pre-clinical AD. A total of 23 articles met the inclusion criteria of the review,...
Cancer associated retinopathy
Abdul Muhyemin Tarin reviews the presentation, pathophysiology and management of this paraneoplastic syndrome. Case presentation A 60-year-old hypermetropic female patient presented with several months’ history of painless blurred vision. Visual acuity (VA) was 6/24 and 6/9-1 in right and left...Traumatic ‘toy’ gun injury leading to permanent vision loss
6 April 2021
| Ehinomen Inegbedion, Doa’a Kerwat, Goncalo Almeida
Pseudoxanthoma elasticum (PXE) is a progressive, inherited disorder of connective tissue that affects the skin, cardiovascular system and retina. Ocular manifestations of the disease are related to Bruch’s membrane, a thin elastic tissue layer located between the retinal pigment epithelium...
Cavernous sinus syndrome
Anatomically the cavernous sinus is a plexus of multiple veins that are connected and within this plexus there are several important vascular and neurological structures. These include cranial nerves III, IV, V1 (and sometimes V2), VI as well as the...Diary from my elective: a Parisian experience
2 December 2019
| Nikolaos Tzoumas
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EYE - General
The author explains how a research institute’s dedication to multidisciplinary collaboration helped him to discover a passion for academic ophthalmology. The elective aspect to the final year of a medical degree, through its change of scenery and immersion into another...