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Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

Innovations in ophthalmology: what can the innovations of the past teach us about tomorrow?

BUOS Prize Essay – 2nd prize winner for 2013 submissions Introduction An essay titled Innovations in Ophthalmology might choose to focus on the history; from cataract couching to femtosecond lasers, ophthalmology has had no shortage of topics worthy of discussion....

Are social media promoting ocular protection in the community?

During the Covid-19 pandemic, many countries worldwide introduced lockdown measures to control infection, causing people to spend more time at home. This resulted in reports of increasing incidences of do-it-yourself (DIY)-related trauma. When the Covid-19 pandemic started in December 2019,...

Effective management of dry eye and ocular surface disease

Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...

Surgery for third nerve palsy (2019)

The authors present a new technique for split muscle medial transposition surgery of the lateral rectus plus union with the distal split stump of the medial rectus. This increases the length of the contracted lateral rectus through the addition of...

My Top Five: Tips for organising and delivering a national ophthalmology educational series

Organising a national teaching series is both deeply rewarding and surprisingly complex. It requires more than just good content – it demands a well-thought-out purpose, seamless logistics, strong communication and meaningful evaluation. Over the past year, I had the opportunity...

Bionic eyes: deciphering the neural circuitry of vision restoration

As the boundaries between technology and biology blur, retinal prosthetics, often dubbed ‘bionic eyes’, present a ground-breaking paradigm shift in addressing blindness. This article delves into the captivating scientific intricacies of these neural interfaces, exploring their mechanisms of action, current...

100 years since Sir William Duke-Elder graduated from the University of St Andrews

With sincere thanks to Andrew King, Ophthalmic Optician and owner of Andrew King Opticians near Glasgow, for his extensive research into Duke-Elder’s life.' Sir William Stewart Duke-Elder. Photo credit: Edward Irvine Halliday, Institute of Ophthalmology. In the world of ophthalmology,...

Long-term outcome of ALPI for plateau iris syndrome

The purpose of this study was to evaluate the long-term outcomes of plateau iris syndrome (PIS) patients treated with argon laser peripheral iridoplasty (ALPI) following YAG laser peripheral iridotomy (LPI). Typical ALPI settings were a spot size of 200 to...

Corneal molecular and cellular biology for refractive surgeon

This is an interesting literature review that looks into the recent advances concerning the corneal molecular and cellular processes that are involved in the wound healing response after excimer laser surface ablation and LASIK surgery. It talks about the complex...

Secondary intraocular lens implantation in children

This is a retrospective study of the medical records of children under the age of 16 who underwent secondary lens implantation for aphakic corrections after previous congenital cataract surgery over a period between January 2000 and December 2010. The study...

Life in the glaucoma laboratory

When people ask me what life in the laboratory is really like, I often pause. On one hand, it is the romantic notion of pushing back the boundaries of science with the daily rhythm of experiments, data and easily obtained...