Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...
Eye research in the UK is underfunded relative to other areas of medical research and general awareness of sight loss and its prevention remains poor, messages that were reinforced in presentations and discussions during a recent research summit meeting in...
1 April 2017
| Sancy Low, Paul J Foster (Prof)
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Glaucoma, Genetics
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...
Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...
The Art is long and Life is short. So goes the dispiriting tag in Latin and flung from day one and at regular intervals thereafter at idle medical students who, inevitably brainwashed, come by graduation to believe that the only...
Eighty-two-year old Janet Smith woke up on the floor. Had she been unconscious? Her head hurt. It was the middle of the night, but in the darkness she suddenly wasn’t sure whether she could see out of her right eye....
The overall goal of the Global Vision Database (GVD) [1] is to develop and deploy new and improved evidence on the prevalence of blindness and vision impairment (VI) globally. It is a repository which allows us to assess the causes...
Open source or crowd-sourcing and crowd-collaboration are concepts almost always associated with software and public online projects such as Wiki project. Never had I imagined that my team would apply the same principle in ophthalmology. Just less than a month...
Microinvasive surgical approaches to primary open-angle glaucoma (POAG) offer minimally traumatic options for effective intraocular pressure (IOP) reduction in appropriately selected glaucoma patients. Increases in laser trabeculoplasty rates and wider adoption of glaucoma drainage device filtration procedures, together with the...
1 April 2015
| Ritu Chaturvedi, Nikhil Cascone, Conrad Yuen, Richard Brown
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Emergency Ophthalmology
The demand for eye casualty appointments has been steadily increasing in the UK, leading to pressures on the hospital emergency services. The incidence of presentations to eye casualty services has been estimated at 20-30 per 1000 per year [1]. Evidence...
1 December 2014
| Anna Pang, Jonathan Park, Anthony Quinn, Roland Ling
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Retina / Uvea / Vitreous
Retinopathy of prematurity (ROP) is a condition that affects the developing retinal vascular system of pre-term babies. If left untreated, ROP can lead to severe visual impairment. The severe visual impairment caused by untreated ROP can be prevented by screening...