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Statins inhibit TGFβ2 mediated fibrotic response in astrocytes
Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...
MicroRNAs in cataract
In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...
Cyclosporine A and pterygium fibroblasts
The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...Glaucoma UK announces United Kingdom & Eire Glaucoma Society (UKEGS) Research Award 2024
Glaucoma UK is delighted to announce that this year’s UKEGS Research Award is now open to UKEGS members. The award, funded by Glaucoma UK and UKEGS, offers up to £50,000 for projects aimed at impacting patient care, scientific advancement, or understanding of glaucoma.A guide to the Multi-Speciality Recruitment Assessment (MSRA) exam
The MSRA exam is a mandatory part of the application for ophthalmology specialist training in the UK. It is a computer-based exam which is designed to assess junior doctors with foundation level competence. It is used for entry to postgraduate...
Problems in Periorbital Surgery: A Repair Manual
This is a multi-author textbook directed at oculoplastic and plastic surgeons carrying out and managing aesthetic eyelid surgery. The authors are well-known and commonly cite their mentor, Clinton (“Sonny”) McCord as the main inspiration behind the textbook. Each section contains...Periocular burns: a literature review of classification, management protocols and outcomes of treatment
The author provides a review of the current literature regarding the principles of classification, management protocols of acute ocular and periocular burns and the role of the burn and oculoplastic surgeon involved in their care. More than two-thirds of facial...
Could medical cannabis be used to successfully treat blepharospam?
This study observed the effect of medical cannabis in benign essential blepharospasm (BEB), in addition to standard botulinum toxin treatment. The study comprised of a retrospective chart review on eligible patients and included information on patient demographics, responses, cannabis history...
Comparison of treatment for hemianopia following stroke
The authors report the screening process and recruitment figures for a randomised controlled trial comparing interventions for post stroke homonymous hemianopia. Interventions included Fresnel prisms, visual search training and standard care (information only). Primary outcome measure was the change in...
Ophthalmic findings following noticeable external injury following forceps delivery
This study prospectively recruited consecutive women following a forceps vaginal delivery of a single foetus in cephalic position over a two-year period. Individual patient consent was waived by the approving body. The neonates received a paediatrician assessment soon after birth....
Handbook of Retinal OCT (Second Edition)
Duker et al. present the second edition of their Handbook of Retinal OCT. It’s an upgrade from their last edition in many respects – there’s an enhanced digital version, the pages have a nice glossy sheen which makes it feel...
