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Maintenance therapy for CMV endotheliitis
Cytomegalovirus (CMV) has been associated with corneal endotheliitis, leading to endothelial cell loss and corneal decompensation. CMV corneal endotheliitis recurrence can affect between 5-60% of eyes after cessation of anti-CMV therapy. Each recurrence of endotheliitis has a detrimental effect on...
A case report of visual loss as a consequence of coeliac disease
The authors present a case of permanent visual loss secondary to occipital lobe calcification in coeliac disease, the first reported such case. The 58-year-old man had been diagnosed with coeliac disease 20 years prior to his visual investigations and had...
Cyclosporine A and pterygium fibroblasts
The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...
Rare case reports of benign optic glioma in adults with clinically aggressive nature
Primary optic nerve gliomas are most commonly benign and occurring in childhood. Malignant optic gliomas occur in adulthood and follow an aggressive course usually leading to blindness and death within months. This paper describes the clinical and histopathological features of...
Diagnostic procedures in vitreoretinal lymphoma.
This paper presented a retrospective review of medical records of HIV negative immunocompetent patients diagnosed with vitreoretinal lymphoma between 1994 and 2012. The aim of the paper was to evaluate the type and number of diagnostic interventions required to confirm...
MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...
Autophagy in lens mitochondria loss
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...What to expect when meeting a statistician
There are a growing number of statisticians working closely with ophthalmologists. They have different training but they are driven by the same goal: to perform high quality evidence based clinical research [1,2]. In a perfect world we would simply conduct...The Case of Dr Bawa-Garba – Do we truly have a ‘no blame’ culture?
Eye News’ medico-legal specialist shares his thoughts on the recent acquittal of Dr Bawa-Garba. On 13 August 2018 the Court of Appeal ruled that Dr Hadiza Bawa-Garba should be reinstated on the UK medical register. The Court of Appeal rejected...My ophthalmic elective: Harvard Medical School
Medical electives are an excellent opportunity to learn, enjoy and explore countries and their healthcare systems. I was grateful to do mine in ophthalmology at Harvard Medical School (HMS). This article will share my personal experience working at HMS with...
