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The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
Advanced vestibular Schwannoma case report
Vestibular Schwannoma is a benign, slow growing tumour which usually presents with unilateral hearing loss. It causes symptoms and findings on ophthalmic examination when the diagnosis is delayed. Ophthalmic findings may be related to the effect of the expanding mass...
Platelet rich fibrin membrane for descemetocele
This case series described the use of a novel technique in the treatment of descemetocele. Three patients developed descemetoceles following infective keratitis with impending risk of corneal perforation. Platelet rich fibrin (PRF) membrane was prepared using 8ml of fresh venous...
MicroRNAs in cataract
In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...
Which factors predispose to pingecula development in a rural Chinese population?
The authors report a cross-sectional study which aimed to determine the prevalence and risk factors for developing pingecula in a rural Chinese population near Shanghai. Nine hundred and fifty-nine persons were recruited from a single village and asked to complete...
Cyanoacrylate vs. fibrin glue
This study compared the safety and efficacy of fibrin and cyanoacrylate glue for refixating the recessed muscle to the sclera in patients undergoing strabismus surgery. The fibrin group (a) included 21 eyes of 15 patients; mean age of 11.6 ±7.49...
Features, treatment and prevention of conjunctival inclusion cysts
Conjunctival inclusion cyst is a rare complication of strabismus surgery and generally develops at the point of muscle reattachment, caused by implantation of conjunctival epithelium. The authors aimed to determine the rate of its development after strabismus surgery and consider...
Saccadic eye movements in young-onset Parkinson’s disease
The objective of this study was to understand control of saccadic eye movements in patients with young onset Parkinson’s disease (YOPD) where onset of disease symptoms appears early in life (<40 years of age). Functional magnetic resonance imaging (fMRI) was...
Delayed angle closure in pseudophakia and repeated intravitreal therapy
The authors report two cases of acute angle closure many years after uneventful cataract surgery and posterior chamber intraocular lens (IOL) implantation. Both patients had neovascular age-related macular degeneration (AMD) and received regular intravitreal injections (24 and 25 injections in...
Visual snow syndrome: a review
Visual snow syndrome (VSS) is a neurological condition characterised by visual phenomena described as dots moving across the visual field. Other visual symptoms can take the form of palinopsia, entopic phenomena, photophobia and nyctalopia. Tinnitus and migraine can be commonly...
Nonarteritic anterior ischaemic optic neuropathy
This review article describes nonarteritic anterior ischaemic optic neuropathy (NAION). This condition is one of the common causes of visual loss in adults. The article uses a good range of references and is divided under the headings of; demographics, clinical...
