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1420 results found

RTP801 as a neuroprotective and axon regenerative treatment

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

Is virtual reality perimetry as reliable as static perimetry in detecting neurological visual field loss?

This study compares agreement between virtual reality perimetry (VRP) and static automated perimetry (SAP) in a variety of neuro-ophthalmological conditions. For this work the Order of Magnitude (OM) VR-based visual field assessment system was used which has been developed by...

Multimodal Retinal Imaging

Understanding of rapidly advancing retinal imaging techniques is important as they have changed the management of retinal conditions considerably. Interpretation of these tests is a vital skill in the armamentarium of every practising ophthalmologist. The book is directed at general...

Using optical coherence tomography angiography to detect MoyaMoya vasculopathy

Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...

Understanding spaceflight-associated neuro-ocular syndrome (SANS): what do we know?

Introduction Formerly known as visual impairment and intracranial pressure syndrome (VIIP), space-related neuro-ocular syndrome (SANS) is defined by a collection of ophthalmic and neurological findings in astronauts after long-term spaceflight [1]. Changes in the eyeball, such as hyperopic shift, during...

Diary from my elective: a Parisian experience

The author explains how a research institute’s dedication to multidisciplinary collaboration helped him to discover a passion for academic ophthalmology. The elective aspect to the final year of a medical degree, through its change of scenery and immersion into another...

Biomaterials and Regenerative Medicines in Ophthalmology (Second Edition)

With advancement in science and technology in the last decade, the role of biomaterials and regenerative medicines has become increasingly important in the management of various ocular disorders. This book highlights the role of biomaterials in the restoration of vision...

Feb/Mar 2014 Quiz 1

History A 55-year-old diabetic male presents with some annoying floaters in his left eye. Slit-lamp examination shows multiple well defined bodies within the vitreous cavity, in an eye otherwise showing background diabetic retinopathy. The patient elects to undergo a vitrectomy....

Scope Eyecare announces winners of Independent Prescriber Bursary Awards 2023

The final of the 2023 SCOPE IP Bursary Awards took place on Thursday 29 June 2023. The award, now in its second year, attracted many entries the quality of which were extremely high.

Quantum technology first in eye disease detection

Scientists are working on a new device that could lead to a reduction in the number of people who go blind from age-related macular degeneration (AMD).

Mechanism of colour vision involvement in multiple sclerosis

There is evidence to show that the optic nerve and retina are affected in multiple sclerosis (MS) even without any clinical evidence or history of optic neuritis (ON). MS without optic neuritis causes colour-vision deficit, however, the evidence for selective...

A case report showing the natural history of papilloedema

The case report describes a 54-year-old woman who developed increased intracranial hypertension due to chronic dural venous sinus thrombosis in the absence of any significant comorbidity. In the years preceding diagnosis, the patient underwent routine diabetic retinopathy screening; however, gradual...