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Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...Working smarter not harder: How to transform eyecare delivery in the United Kingdom (part 1)
Are we doing enough to meet the current demands on ophthalmic services? In part one of a two-part series (see Part 2 here), Rosalind Harrison takes a look at how efficiency has been improved in eyecare services in the US....
Medial rectus surgery with development delay
The long-term results of bilateral medial rectus surgery are evaluated in 42 children with development delay. Mean age pre-surgery was 2.9 years with a mean follow-up of 4.6 years. Mean angle of esotropia was 44.29±13.9PD; 57% achieved surgical success; 31%...Genetic profiling for personalised healthcare solutions in AMD – an update
Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...Grading of ocular inflammation in uveitis: an overview
Anterior uveitis is the commonest form of uveitis, which can lead to severe morbidity if not treated appropriately [1]. Data from general ophthalmology practices suggest around 90% of uveitis encountered by comprehensive ophthalmologists is anterior uveitis [2]. Intermediate (vitreous), posterior...
Outcomes after surgical excision of limbal dermoid
The authors aimed to report the visual and refractive outcomes and complications of simple excision of limbal dermoid (LD) sparing the visual axis and Descemet’s membrane in children aged ≤8 years. This was a retrospective review over 2000-2019 including 19...
Changes in corneal endothelial layer after strabismus surgery
The purpose of this study was to investigate the changes in the corneal endothelial layer by specular microscopy after surgery in patients with horizontal and oblique strabismus. Eighty-three eyes of 56 patients were evaluated prospectively. There were three subgroups: one...
Prevalence and risk factors for ROP in Saudi Arabia
This study aimed to establish the prevalence of retinopathy of prematurity (ROP) among high-risk neonates in a tertiary centre, identify the most commonly associated risk factors and highlight the benefits of early treatment of type 2 ROP and ROP milder...
Does pregnancy cause progression of keratoconus in previously cross-linked corneas?
This is a prospective study involving 24 eyes of 19 patients with stabilised or regressed keratoconus after a successful accelerated cross linking (A-CXL) treatment. Patients were recruited at a routine follow-up visit in the first month of their pregnancy. The...
Does religious fasting affect intraocular pressure or retinal parameters?
Nearly one billion Muslims fast every year during the month of Ramadan. Due to the difference between the lunar and solar calendars, religious fasting time can range from 11 to 17 hours per day. This prolonged abstinence from food and...
Use of botulinum toxin A in the treatment of intermittent exotropia
In this prospective cohort study, the authors aimed to evaluate the efficiency of botulinum toxin A (BTA) injection in the treatment of intermittent exotropia (IXT) and examine factors affecting treatment outcomes. Seventy-four patients diagnosed with any type of IXT were...
