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CSD-OCT detection of minimally visible retinoblastoma
This paper reports minimally visible tumour recurrence that was detectable on spectral domain OCT (SD-OCT) in a two-month-old infant who had a diagnosis of bilateral familial retinoblastoma. The infant was treated with IVC for six cycles with vincristine, etoposide and...
Hemianopia or visuospatial neglect: differences in information processing
It is widely reported that visuospatial neglect and hemianopia may be superimposed, and disentangling the two conditions can be pose difficulties for clinicians. The authors of this paper explored the differences in implicit information processing which is effective in patients...
Somatostatin protects retinal pericytes
Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...
SD-OCT detection of minimally visible retinoblastoma
This paper reports minimally visible tumour recurrence that was detectable on spectral domain OCT (SD-OCT) in a two-month old infant who had a diagnosis of bilateral familial retinoblastoma. The infant was treated with IVC for six cycles with vincristine, etoposide...
Conjunctival mapping biopsies in sebaceous carcinoma
This is a retrospective review of conjunctival mapping biopsies in patients with periocular sebaceous cell carcinoma. The authors reviewed the biopsy technique and outcomes of 45 patients who had mapping biopsies performed over a 25-year period. A total of 429...
MicroRNAs in cataract
In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...
Comparison of treatment for hemianopia following stroke
The authors report the screening process and recruitment figures for a randomised controlled trial comparing interventions for post stroke homonymous hemianopia. Interventions included Fresnel prisms, visual search training and standard care (information only). Primary outcome measure was the change in...
Use of RAPDx device with optic nerve disease
The authors have previously reported on use of the RAPDx device for evaluating relative afferent pupillary defects (RAPD). RAPDx objectively determines the magnitude of RAPD by presenting light stimuli alternately to pairs of eyes with laterality. The parameters of amplitude...
Proprioception and ptosis
This is a small prospective study investigating the effect of proprioceptive factors on upper lid height. Eight unilaterally anophthalmic patients with ocular prostheses and normal lid heights had standardised photographic measurements taken of their eyelid and brow positions. Three sets...
Treatment of Sjogren’s Syndrome dry eye in mouse model
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...
PD-1 and retinal ganglion cell death
Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...
