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Ovarian hormones drive onset of Sjogren’s disease in mice

1 December 2014 | | Cornea / External Eye Disease | Sjögren’s Syndrome, lacrimal glands, sex hormones, cytokines, anti-Ro/SSA, anti-La/SSB, NOD.B10.H2b
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...

PERG as a visual prognosticator in chiasmatic tumours

1 April 2014 | | Ophthalmology | chiasmal compression, pattern electroretinogram, sellar tumour
Pattern electroretinogram (PERG) allows assessment of ganglion cell function and may therefore be used to assess anterior visual pathway dysfunction. This prospective non-randomised study assessed PERG before and after surgical removal of tumours in and around the sellar region compressing...

Strengthening eye care services in Botswana through the Botswana-Addenbrooke’s Abroad VISION 2020 LINK

1 April 2016 | | Cataract and Refractive, Cornea / External Eye Disease, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Ophthalmology, Oculoplastics, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous, AMD, Emergency Ophthalmology
The VISION 2020 LINK between Botswana and Addenbrooke’s Abroad has been running for 10 years. With support from the VISION 2020 LINKS Programme two-way exchange visits were undertaken leading to the formation of the first formal international partnership under Addenbrooke’s...

Neonatal hypoxic ischaemic encephalopathy with imaging abnormalities in the occipital lobe – how to counsel the parents

5 April 2022 | | Ophthalmology, Neuro-Ophthalmology, Imaging
Case A baby boy, with a background of intrauterine growth restriction, was born at 37 weeks and three days gestation via forceps delivery. The baby was born in poor condition, with low heart rate, poor respiratory rate, poor colour and...

In conversation with Charles Leclercq (ARxVision)

5 October 2022 | | Ophthalmology, ONLINE EXCLUSIVE ARTICLES
Julian Jackson (Founder and Director, VisionBridge) spoke to Charles Leclercq (CEO, ARx) about the ARxVision, a wearable device that captures the world around us through audio and artificial intelligence to empower blind and low-vision individuals. You can read the Eye...

Corneal keloid: Report of natural history and Outcome of Surgical Management in Two Cases

1 February 2014 | | Cornea / External Eye Disease
Corneal keloids are rare and typically reported following trauma (including post-surgical) and has been reported without any trauma or previous surgery. A corneal keloid differs from a hypertrophied scar in that it occurs months/years after the injury, enlarges over time...

Acute dacryoadenitis secondary to COVID-19

4 October 2023 | | Ophthalmology, COVID-19
Acute dacryoadenitis is defined as the rapid onset of discomfort and swelling of the lacrimal gland, classically giving rise to an S-shaped ptosis [1]. Dacryoadenitis is the most common cause of a painful mass in the lacrimal gland in young...

Beyond 2020 Episodes 01-03

5 June 2023 | Ophthalmology
Introduction Working in remote, Amazonian villages, the Andean Medical Mission (AMM) have made progress into eliminating avoidable blindness in this small corner of the globe and have produced a video series, Beyond 2020, to share what they’ve learned over 12...

Eye drop reminder apps

1 April 2016 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
There are quite a few apps in both the iPhone and Android app stores designed to help patients remember to take their eye drops. The goal here was to select an app suitable to recommend to patients. Ophthalmic specific apps...

In conversation with Imran Rahman (CHEC)

1 August 2022 | | Ophthalmology, COVID-19
Imran Rahman, CEO and Consultant Ophthalmologist, CHEC, spoke to Chris Henson about tackling the COVID-19 backlog, community-based support for the NHS, and the digitisation of healthcare. Without major intervention, will we ever see an end to the COVID-19-induced NHS backlog,...

What can we learn from Jimmy McGill?

3 October 2022 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
A few months ago, my eldest son got me interested in a Netflix series called “Better Call Saul”. This is a spin-off from another series called “Breaking Bad”, although I confess to not having seen any of those episodes as...

Study reveals increase in Charles Bonnet Syndrome symptoms due to COVID-19

12 February 2021
A study published today in BMJ Open Ophthalmology has shown the impact of COVID-19 on those already experiencing vivid hallucinations as a result of Charles Bonnet syndrome (CBS).