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Sustained elevation of extracellular ATP in chronic glaucoma
Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...
Brn3b neuroprotective effect in rat glaucoma model
An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...
Reduced angle after BT for postop diplopia test
The authors undertook a retrospective study to evaluate the extent of reduced deviation after Botulinum toxin (BT) when used as a postoperative diplopia test. They evaluated effect in 39 patients: 32 exotropia and seven esotropia. The same BT dose was...More action on sepsis needed as NHS Ombudsman still seeing same failings a decade on
The UK’s Health Ombudsman has warned that sepsis is still taking too many lives due to the same hospital failings we were seeing over ten years ago.Shared vision: Father and son navigate life with glaucoma together
Glaucoma UK is a charity dedicated to supporting people living with glaucoma across the UK. They’re getting ready for Glaucoma Awareness Week, an annual awareness raising campaign, which is running from 24–30 June.Cataract surgery supervision
Senior trainees supervising other more junior trainees’ cataract surgery is a skill which needs to be taught and developed with care. It is beneficial for senior trainees as it provides an opportunity to develop supervision techniques prior to consultancy and...The invisible touch: a VISION 2020 LINK with Indonesia
Indonesia’s population, the world’s fourth largest, is spread across 6,000 inhabited islands. Whilst some areas (e.g. Kalimantan, Papua) are relatively sparsely populated, Java is the world’s most densely populated island, with twice the population of the UK in half the...Life as a Global Citizen Consultant Ophthalmologist: a personal view of working in Scotland and Tanzania
Global Citizen post - a new challenge I was looking for a new challenge. I had been in the same consultant post with a subspecialty interest in paediatrics and strabismus for 17 years and was rattling around in an empty...Development of retinoblastoma services in Zimbabwe
Zimbabwe recognised the need for a paediatric ophthalmology service almost 20 years ago. The economic uncertainty in the country made it difficult to secure financial support, so initial funding came through local donors. Equipment – including vision charts, ophthalmoscopes and...Johnson & Johnson announces lead vaccine candidate for COVID-19
Johnson & Johnson has announced the selection of a lead COVID-19 vaccine candidate and the rapid scaling of its manufacturing capacity with the goal of providing global supply of more than one billion doses.
Risk factors for lens dislocation post cataract surgery
This retrospective cohort study in Korea assessed the risk factors for intraocular lens (IOL) dislocation. They used national data of 2,162,191 patients who had had cataract surgery between 2009 and 2016. They excluded any patient who had an IOL dislocation...
