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5478 results found

Treat-and-extend regimen in treatment of patients with type 3 neovascularisation

Type 3 neovascularisation, also known as retinal angiomatous proliferation is a distinct subtype of neovascular AMD characterised by intraretinal neovascularisation. This retrospective study included 17 eyes diagnosed with type 3 neovascularisation who were changed from pro-re-nata (PRN) based treatment regime...

Orbital sphenoid sinus trauma: a rare trauma case

With a high complication and mortality rate, intra-sphenoidal and transorbital trauma poses a high complication rate and remains challenging to manage. Numerous key structures run nearby such as: the optic nerve, internal carotid arteries and ophthalmic arteries. The authors present...

Amblyopia prediction using Plusoptix

The aims of this study were to evaluate Plusoptix performance in amblyopia prediction, to examine the best readings for that prediction and to determine if it is sufficient to have one measure or more. Data were collected in a two-year...

Intravitreal Ziv-Aflibercept: safety analysis

Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...

How does low-concentration atropine reduce progression of myopia?

This is a double-blind, randomised, placebo-controlled trial evaluating the effects of low-concentration atropine (0.05%, 0.025%, 0.01%) on ocular biometrics of myopic children. The aim is to determine what aspect of ocular biometrics low-concentration atropine influenced in reducing the progression of...

Characteristics of limbal lymphatic vasculature on confocal microscopy

This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...

Review of pathogenesis of Acanthamoeba keratitis

In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...

Cutaneous malignant melanoma metastasis to pseudophakic lens

Metastases to the eye and orbit are rare and intraocular cutaneous malignant melanoma metastasis (ICMM) is exceedingly rare, representing around 5%. There have only been three previous cases of ICMM to the lens in the literature, all of which presented...

Oculofacial plastic surgery – is antibiotic prophylaxis required?

This is a randomised, controlled, unmasked clinical trial evaluating whether topical antibiotic prophylaxis reduces the rate of infection after oculofacial plastic surgery compared to a non-antibiotic ointment. A total of 401 participants over the age of 18 were recruited, with...

Aspirin and upper lid surgery

This is a double-blind randomised controlled trial of preoperative aspirin versus placebo in patients undergoing upper lid blepharoplasty or ptosis surgery. All enrolled patients were already taking aspirin and no other anti-platelet or anticoagulant drugs. All patients either had no...

PI drops and respiratory change during surgery

Five percent povidone-iodine (PI) topical application to the eye has been observed to cause apnoea under general anaesthetic (GAS). The authors designed a randomised single-blinded controlled trial to evaluate changes in respiration caused by PI eye drops. They recruited 100...

OCT choroidal signs for congenital retinal pigment epithelium hypertrophy

Congenital hypertrophy of the retinal pigment epithelium (CHRPE) on ocular coherence tomography (OCT) has the characteristic sign of RPE thickening and hyper reflectivity. However, the underlying choroid characteristics remain under researched. This retrospective study utilised data from an ophthalmic oncology...