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395 results found

Progression of macular atrophy on long-term anti-VEGF therapy for AMD

This retrospective study evaluated the progression of macular atrophy in 53 eyes of 53 patients receiving AntiVEGF Therapy for age-related macular degeneration (nAMD), for at least six years. None of the patients had any macular atrophy (MA) at presentation. MA...

Quality of life concerns after uveal melanoma diagnosis

The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...

Improving reading of fundus photographs in an emergency setting

The first phases of the FOTO-ED study found that emergency providers perform significantly better with fundus photography than with direct ophthalmoscopy in the detection of fundus abnormalities. The authors hypothesised that by providing additional training to emergency providers, this would...

Optimising treatment with transscleral cyclophotocoagulation

This study compares the outcomes of transscleral diode laser cyclo-photo-coagulation with the treatment parameters used. This was a retrospective chart review of a random sample of diode laser procedures using the G-probe over 10 years for uncontrolled glaucoma. The main...

IAC vs. IVC chemotherapy for RB

This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...

Prism adaptation test in acquired non-accommodative esotropia

This study investigated factors related to the increase in prism adapted angle in patients with acquired non-accommodative comitant esotropia (ANAET) who had strabismus surgery based on the results of a short prism adaptation test (PAT) and evaluated their outcomes. Short...

Penetrating keratoplasties in infants

This retrospective review looked at endothelial cell counts (ECC) following penetrating keratoplasties (PKP) performed in infants within the first year of their life. One hundred eyes of 71 patients had their first PKP during the study period (1998-2013). In 30%...

ICG TTT for retinoblastoma

Transpupillary thermotherapy (TTT) is a specific form of ocular TT using infrared radiation (diode laser). Indocyanine green (ICG) is also used to achieve the optimal phototherapy effect in eyes with minimal pigment. Twenty-one patients with 42 retinoblastomas in 30 eyes...

Expert vs. non expert grading of ROP from digital video images

The primary purpose of this study was to determine whether digital video images of the retina obtained using an indirect ophthalmoscope imaging system could be accurately graded for zone and stage of retinopathy of prematurity (ROP) and the presence of...

Uveitis in HIV infected persons

Before the advent of highly active antiretroviral therapy (HAART), uveitis, in particular cytomegalovirus (CMV) retinitis, was the most common cause of visual loss in patients with AIDS. HAART has altered the cause of ocular disease in HIV infected individuals by...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

Unilateral central scotoma following dengue fever

Case report A 16-year-old Caucasian male was referred to the eye casualty at Nottingham University Hospitals NHS Trust by the infectious diseases unit in September 2013. He gave a history of photophobia, pain on eye movements and central blurred vision...