You searched for "choroid"
Macular pigment in relatives of AMD patients
3 April 2024
| Kurt Spiteri Cornish
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Retina / Uvea / Vitreous
Blue light causes photo-oxidative retinal injury and macular pigment (MP), with lutein, zeaxanthin and mesozeaxanthin as the main components, as a filter that protects the macula from this damage. Previous studies indicated that low levels of macular pigment optical density...
A mouse model for uveal melanoma
1 December 2014
| Graham Wallace
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Ocular Pathology and Oncology
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Grm1, melanoma, metabotropic glutamate receptor, mouse model, uveal melanoma
Uveal melanoma (UM) is the most common malignant tumour arising within the eye and is a severe threat for both sight and life, due to a high risk of metastasis. There are no animal models of UM, but the Tg(Grm1)...
Complement factor B polymorphism and the phenotype of early age-related macular degeneration
1 August 2014
| Huw Edward Oliphant
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Retina / Uvea / Vitreous
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...
Risk factors and untreated POAG
1 December 2013
| Lorraine North
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Glaucoma
The authors examined 50 untreated open angle glaucoma patients to determine if there was an association between the level of glaucomatous damage and documented risk factors. In this study the authors measured the extent of morphologic and functional glaucomatous damage...
In conversation with Professor Usha Chakravarthy (2018)
Professor Chakravarthy popped by the Eye News stand at the 2018 Royal College of Ophthalmologists Annual Congress after her excellent Bowman Lecture. She gave us a summary of her presentation, which looked at how our understanding of AMD has changed...Moorfields Education: Hot topics in comprehensive ophthalmology
7 February 2025
Hot topics in comprehensive ophthalmology is a course for people who work in the field suitable for comprehensive/general ophthalmologists, urgent care and primary care, optometrists and nurse practitioners. This is an update on common themes which appear in the comprehensive...
Lessons from an unusual case of syphilis
3 August 2023
| Ryian Mohamed, Shaman Dolly, Jonathan Than, Shweta Anand
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EYE - Vitreo-Retinal
The rise of syphilis transmission rates over the past two decades has been one of public health’s great puzzles. In the UK, the situation has reached epidemic levels, with a 126% increase between 2013 and 2018 [1]. We present a...
CHEC Preston celebrates key milestone with 3000th patient
Community healthcare provider marks major milestone for patient choice and equitable access.BRASCRS 2025
28 May 2025
-31 May 2025
XXXII Congress of Cataract and Refractive Surgery
Pigmented paravenous retinochoroidal atrophy
4 December 2024
| William Spackman, Tun Giap Tan, Stephen Turner
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EYE - Imaging, EYE - Vitreo-Retinal
Presentation A 46-year-old Caucasian female was referred to the eye clinic by her local optician following a routine sight test. She was noted to have pigmentary retinal changes in both eyes but was asymptomatic with no visual complaints. At presentation...
Paraneoplastic optic neuropathy features
1 August 2019
| Jonathan Chan
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Neuro-Ophthalmology
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PNS antibodies, paraneoplastic optic neuropathy, paraneoplastic syndrome (PNS)
This is a retrospective review of seven patients diagnosed with paraneoplastic optic neuropathy (PON) between January 2015 and June 2017. Five patients had a history of primary malignancy, including papillary thyroid carcinoma, type B thymoma, testicular seminoma and lung carcinoma....
Validity of coding in neuro-ophthalmology within large administrative datasets
7 April 2021
| Lauren R Hepworth
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Neuro-Ophthalmology
A systematic review of validation studies of the International Classification of Disease (ICD) coding system, ICD-9 and ICD-10 is presented by the authors. Three searches were conducted based on three concepts, firstly health administration claims and ICD codes, secondly diagnostic...