You searched for "epithelium"

333 results found

Outcomes after surgical excision of limbal dermoid

The authors aimed to report the visual and refractive outcomes and complications of simple excision of limbal dermoid (LD) sparing the visual axis and Descemet’s membrane in children aged ≤8 years. This was a retrospective review over 2000-2019 including 19...

A step-by-step approach to the diagnosis and management of Sands of Sahara Syndrome

Sands of Sahara syndrome (diffuse lamellar keratitis) is a rare postoperative complication of Laser in situ keratomileusis (LASIK). Its estimated prevalence is reported to be 2-4% among LASIK cases [1], despite that, it is more likely to be encountered by...

Lacrimal gland carcinoma outcomes

This is retrospective review of outcomes of lacrimal gland epithelial tumours treated between 1972 and 2014 at Moorfields Eye Hospital. Seventy-nine patients were reported, comprising 53 adenoid cystic carcinomas, 15 primary adenocarcinomas and 11 carcinomas ex-pleomorphic adenoma. The authors compare...

Multimodal imaging in wet AMD

This novel study set out to determine grader agreement levels of various retinal imaging techniques, commonly used in the diagnosis of wet age-related macular degeneration (AMD). Images from 52 eyes were by examined by two different observers. All images were...

Corneal thickness in patients with diabetic peripheral neuropathy

This cross-sectional study assessed corneal thickness in association with diabetic peripheral neuropathy (DPN) severity. The study also tried to identify the layer of the cornea most affected by DPN status. Performed at the University of Michigan the study included three...

Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis

This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...

Boston type I keratoprosthesis for limbal stem cell deficiency

Boston type I keratoprosthesis (KPro) long-term outcomes were compared in patients with and without limbal stem cell deficiency (LSCD) in this retrospective study. In the 11 year period 68 procedures were performed in individuals with LSCD, and 105 procedures in...

Risks factors for graft preparation failure in DMEK

Diabetes mellitus (DM) makes it more difficult to prepare descemet membrane epithelial keratoplasty (DMEK) grafts due to the ‘stickiness’ of Descemet’s membrane. This retrospective study examined a classification system, where donors were scored points according to their DM related risk...

Lacrimal gland carcinoma

This is a major review of the management of lacrimal gland carcinoma, focusing mainly on adenoid cystic carcinoma. Relevant literature published in English since 1970 was included amounting to some 40 articles after filtering. Overall mortality for all lacrimal gland...

Comparison of SS-OCT and SD-OCT in polypoidal choroidal vasculopathy

Swept source OCT (SS-OCT) is known to have a longer wavelength than spectral domain OCT (SD-OCT), allowing deeper penetration into retinal and choroidal layers. The aim of this study was to investigate whether SS-OCT is superior to SD-OCT in imaging...

Tear film thickness after treatment with artificial tears in patients with moderate dry eye disease

In recent years artificial tear drops addressing tear film osmolarity have come onto the market. Increased tear evaporation and reduced tear volume results in tear hyperosmolarity. This triggers an inflammatory process leading to apoptosis of goblet and epithelial cells. Trehalose,...

Ovarian hormones drive onset of Sjogren’s disease in mice

Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...