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1729 results found

Combined Vismodegib and Mohs surgery

1 April 2019 | | Oculoplastics
This is a report of eight patients with locally advanced periocular basal cell carcinoma who were treated with Vismodegib prior to Mohs micrographic surgery. The rationale for the combined treatment plan was that long-term Vismodegib is poorly tolerated due to...

Importing iron to the retina

1 October 2017 | | Retina / Uvea / Vitreous | Age-related macular degeneration (AMD), Ceruloplasmi, Hepcidin, Hephaestin, Iron, Retina, Zip14, Zip8
In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...

Neovascular AMD: fresh recommendations underline standards of best practice

1 December 2013 |
The management of neovascular age-related macular degeneration (nAMD) has advanced dramatically over the past seven years, with the introduction of targeted new therapies that successfully maintain or improve vision in a majority of affected individuals. It’s a fast moving field,...

Charles Bonnet Syndrome emerges from the shadows

10 November 2020
There has been a ground-breaking response to the online Charles Bonnet Syndrome Patient Information event on 16 November.

The disease burden of AMD

1 December 2015 | | Retina / Uvea / Vitreous
In this multi-centre, prospective, observational, time and motion study the authors assessed the time burden of managing wet AMD for doctors, staff, patients and caregivers in the USA. The study spanned the period from March 2011 to August 2012, and...

AOP launches research into key reforms proposed for primary eye care services in Wales

19 May 2023 | AOP, eyecare services, primary, Wales
The Welsh Government put forward proposals for major reforms of primary eye care services

A missed intraocular telescope – an opportunity to re-focus the evidence

4 February 2021 | | Ophthalmology, Cornea / External Eye Disease, Retina / Uvea / Vitreous, Imaging
Intraocular telescopes allow magnification of the image so that it would be projected into a larger area of the macula, this makes the central defect caused by dry age-related macular degeneration (AMD) smaller. The most common approach is a Galilean...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Advances and developments in medical retina

1 February 2019 | | Ophthalmology, Retina / Uvea / Vitreous
The author provides an update on late breaking clinical trial results in neovascular age-related macular degeneration (nAMD) and presentations on diabetes management from the American Academy of Ophthalmology Retina Subspecialty Day, held during the Academy’s annual meeting in Chicago, October...

LambdaVision aims to refine process for in-space manufacturing of artificial retinas through ISS National Lab-sponsored investigation

1 February 2024 | ISS, retinal, artificial, LambdaVision, industry, innovation, retinitis pigmentosa, RP
Approximately 1.5 million people worldwide are affected by retinitis pigmentosa, a rare genetic disorder that causes vision loss. Currently there is no cure, but researchers from LambdaVision are turning to the International Space Station (ISS) National Laboratory to look for...

SCONe Project seeks participants for patient and public involvement group to revolutionise AMD research

29 April 2024 | baljean dhillon, SCONe, project, research, scotland, edinburgh, AMD, call to action
The SCONe project, run by optometrists, ophthalmologists, and researchers from the University of Edinburgh, and funded by Sight Scotland, is appealing for participants to take part in a Patient and Public Involvement (PPI) group focused on revolutionising the detection and management of Age-Related Macular Degeneration (AMD).

Understanding and confronting bacterial endophthalmitis

2 December 2019 | | Ophthalmology, Cornea / External Eye Disease, Emergency Ophthalmology, Retina / Uvea / Vitreous
Abdus Samad Ansari highlights the importance of early recognition of this condition using an unusual presentation. Endophthalmitis is a medical emergency with devastating consequences. Despite adequate treatment, severe cases frequently result in permanent blindness. Endophthalmitis involves inflammation of both the...