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4041 results found

Sex hormones in males and females with central serous chorioretinopathy

This study was aimed to assess the role of sex hormones in male and female patients with central serous chorioretinopathy (CSC), a disease with a pronounced male predilection. Two hundred and six patients, 183 males (mean age 52, median 52,...

Glaucoma medications and ocular surface disease

This literature review examined ocular surface disease (OSD) associated with glaucoma medication. The authors examined the prevalence of features and management guidelines glaucoma medication associated OSD. Fifty-eight articles published within the past five years are included in this review and...

Practice patterns of uveal melanoma management with Iodine-125 brachytherapy

With the 2006 Collaborative Ocular Melanoma Study Group (COMS) study demonstrating no difference in survival outcomes for participants randomised to either iodine-125 brachytherapy or enucleation, the majority of primary uveal melanomas in the United States are now treated with brachytherapy....

Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy

In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...

Evisceration in India: demographic and clinical trends from a large multicentre cohort study

In this multicentre cohort study, the authors investigated a total of 2071 patients who underwent evisceration with primary implant placement over a six-year period at four tertiary eyecare centres in India. Out of 1,345,480 new ophthalmic presentations during the study...

Optic disc pit maculopathy: an optical coherence tomography study

This was a single-centre, retrospective observational case series that aimed to analyse the change of optical coherence tomography (OCT) characteristics in the natural course of optic disc pit maculopathy (ODP-M) and their effects on visual acuity. Twenty-two eyes of 22...

Clinical presentation, management, and outcomes in posterior segment open globe injuries

This is a retrospective, non-comparative, interventional case study of patients presenting with scleral and corneoscleral wounds covering a five-year period. It reports the clinical presentation, management, and factors affecting the outcomes of posterior segment open globe injuries (OGI) in 2360...

Ocular manifestations of Whipple’s disease

In this retrospective review of 217 patients with Whipple’s disease (WD), the authors reviewed the presentations of those with ocular manifestations. Ocular signs of WD are under recognised, frequently resulting in misdiagnosis and mismanagement. Mayo Data Explorer, a Mayo Clinic...

Does the length of the school day have a role in age of myopia onset?

The authors prospectively collected the refractive data of myopic adults attending recruiting dispensing optician or ophthalmologist sites. Participants were recruited consecutively, giving verbal informed consent. Sites included a mix of urban and rural areas across eight sites. The following data...

Improved quality of life in children with allergic conjunctivitis and their parents with anti-allergic therapy

This prospective intervention study investigated the change in quality of life in child-parent pairs with allergic conjunctivitis (AC) on anti-allergic therapy. From September 2020 to May 2021, AC child-parent pairs and healthy child-parent pairs were recruited in Guangzhou, China. Children...

Balancing early and late surgical intervention for congenital nasolacrimal duct obstruction

This retrospective study investigated the incidence of anisometropia and amblyopia by age of congenital nasolacrimal duct obstruction (CNLDO) resolution. At Seattle children’s hospital, between 2007 and 2017, the outcomes of children with early versus late spontaneous resolution of CNLDO were...

OCTA in diabetic macular oedema treated with intravitreal aflibercept (DOCTA Study)

Central vision loss due to diabetic macular oedema (DME) can be attributed not only to presence of the macular oedema itself but also, in some cases, to alterations of the foveal avascular zone (FAZ). The DOCTA trial was a longitudinal,...