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Stromal cell alignment in damaged cornea

Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...

The dynamic nature of orbital cavernous haemangiomas

This paper seeks to address the question of how much do orbital cavernous haemangiomas actually change over time, and if there are any identifiable factors which can predict which lesions will grow and which will remain stable. In particular, if...

RTP801 as a neuroprotective and axon regenerative treatment

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

Inhibiting high-risk corneal allografts

The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...

The Case of Dr Bawa-Garba – Where does the buck stop?

The case of Hadiza Bawa-Garba has left all of us in the UK medical profession with an uncomfortable taste in our mouths. We all know that we work under pressure and we will inevitably make mistakes. We all know that...

UKISCRS 47th Annual Congress Preview

Check out the Eye News preview for UKISCRS' 47th Annual Congress in London, 1-3 November.

‘Step Up For Nystagmus’ this Nystagmus Awareness Day

Monday 20 June, the Nystagmus Network marks Nystagmus Awareness Day by asking supporters to ‘Step Up For Nystagmus’ to raise awareness of this complex visual impairment.

90% of NHS trusts now have electronic patient records

The NHS has met the government’s target for 90% of trusts adopting electronic patient records (EPR) in hospitals ahead of schedule.

Surgery for third nerve palsy (2019)

The authors present a new technique for split muscle medial transposition surgery of the lateral rectus plus union with the distal split stump of the medial rectus. This increases the length of the contracted lateral rectus through the addition of...

Superior oblique tuck procedure

A retrospective study was conducted of superior oblique (SO) tuck as a primary and secondary surgery over a 25-year period involved 162 eyes of 162 patients. Two thirds were male. Mean age at surgery was 45.94 years. The left eye...

Adjustment under topical anaesthesia in children

This is a study of 19 cases of strabismus surgery using topical aesthetic and intraoperative adjustment in selected children. The study included 14 males and five females with mean age of 12.68 ±2.5 years (range 8-16). Five were esotropia and...

Long-term outcome of scleral-sutured posterior chamber intraocular lens

This is a retrospective review of 392 consecutive cases in 349 patients who had scleral-sutured intraocular lens (IOL) due to aphakia, subluxated or luxated IOL, over a 10-year period in one centre from Barcelona. Preop and postop data were collected...