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Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy
In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...
Is there an association between dry eye disease and depression and anxiety?
Dry eye disease is a widespread ocular surface condition (prevalence 5.5-33.7%) that has been previously linked to systemic diseases, such as Sjogren, rheumatoid arthritis and more recently possibly also depression, in small population-based studies. The authors’ aim was to investigate...Childhood glaucoma
When a child is given a diagnosis of glaucoma, the impact upon that child and their family is enormous; equivalent to the diagnosis of a cancer [14]. This article outlines the knowledge, techniques and approaches that offer solutions to the...What to expect when meeting a statistician
There are a growing number of statisticians working closely with ophthalmologists. They have different training but they are driven by the same goal: to perform high quality evidence based clinical research [1,2]. In a perfect world we would simply conduct...
How common are ocular motor cranial nerve palsies following TBI?
This retrospective cohort study aimed to report the incidence of ocular cranial nerve palsy as a result of traumatic brain injury (TBI). Patients were identified using an insurance database using codes from the International Classification of Disease 9th and 10th...
Mitomycin C versus 5-FU as an adjunctive treatment for trabeculectomy
Antifibrotic agents are used during trabeculectomy (TRAB) to improve long-term surgical success by reducing fibrosis of subconjunctival and episcleral tissue. The purpose of this meta-analysis was to directly compare the efficacy and safety of the two most frequently used antifibrotic...It’s not always GCA
Giant cell arteritis (GCA) is an immune mediated granulomatous inflammatory disease that affects muscular middle or large sized arteries. It is considered as a continuation of polymyalgia rheumatica (PMR) when the severity of the disease has increased. It is the...
Medial rectus recession in Grave’s orbitopathy
The purpose of this retrospective study was to analyse the surgical effect / success rate of recession of the medial rectus in 90 patients with horizontal diplopia. Mean age was 52.5 ±9.4 years. Of that 24% had unilateral medial rectus...Coming to terms with AI
A machine might be called intelligent if its response to questions could convince a person that it was human, a test proposed by Alan Turing in 1950 [1]. The author considers potential applications of artificial intelligence (AI) using machine learning...
