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Ocular Trauma Scores in paediatric open globe injuries

This is a retrospective case series of 71 open globe injuries in children of less than 18 years of age, with a minimum follow-up period of one year, between 1 September 1992 to 31 July 2011, from the Eye Department...

Optical coherence tomography in patients exposed to vigabatrin

Vigabatrin is used to treat epilepsy and can lead to increased levels of gamma-aminobutyric acid (GABA) in the brain and in the retina leading to binasal visual field defects. Although not the first line of treatment for adults it is...

Sclerotomy suturing

This was a retrospective review of 589 consecutive cases of patients who underwent 23-gauge tranconjunctival pars plana vitrectomy. Cases were split into Type 1 vitrectomies (macular hole, ERM and simple vitreous haemorrhages) and Type 2 cases which were more complex...

RAPD in glaucoma screening

A study was conducted to investigate the relative afferent pupillary defect (RAPD) by swinging flashlight as a potentially useful screening test for glaucomatous optic neuropathy. The authors recruited 107 subjects with or without glaucoma from a clinic population. A medical...

Using frequency doubling technology perimetry to identify Alzheimer’s disease early

Alzheimer’s disease is widely reported to be associated with deficits in visual function. Visual disturbances include impaired stereopsis, contrast sensitivity and motion detection. Deficits specific to the magnocellular pathway (MGC) have been identified in Alzheimer’s disease. This article compares the...

Antibiotic prophylaxis after intravitreal injections

The use of topical antibiotics as prophylaxis after intravitreal injections is a contentious issue, especially now with increasing use of intravitreal anti-VEGF agents. In the Wills Eye Institute, prior to May 2011, all patients undergoing intravitreal injections in the office...

Sutureless 27-gauge needle intrascleral intraocular lens implantation

The authors report on a prospective, non-comparative, interventional case series of patients undergoing sutureless intrascleral fixation of a posterior chamber three piece intraocular lens (IOL) using a 27-gauge needle for docking. Sutureless techniques have the advantage of not having complex...

Intracameral bevacizumab as an adjunct to trabeculectomy

This is a 12-month, prospective, randomised, double-masked, placebo-controlled trial of patients who were not controlled medically with open angle glaucoma and scheduled for a primary trabeculectomy. Patients were recruited and randomised during the period between April 2009 and November 2010....

Direct endoscopic probing for congenital lacrimal duct obstruction

The most common treatment for congenital lacrimal duct obstruction (CLDO) is probing, which is traditionally a blind procedure. Previous literature reports success rates between 78-92%. The authors of this retrospective non comparative case series reviewed the success rates of probing...

PERG as a visual prognosticator in chiasmatic tumours

Pattern electroretinogram (PERG) allows assessment of ganglion cell function and may therefore be used to assess anterior visual pathway dysfunction. This prospective non-randomised study assessed PERG before and after surgical removal of tumours in and around the sellar region compressing...

New mouse model of diabetes mellitus

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...

Prostaglandin levels in femto cataract surgery

Following previous reports of pupil size decrease after femtosecond treatment, the authors compare levels of prostaglandins in patients undergoing femtosecond assisted cataract surgery with those having routine cataract surgery. Patients with inflammatory eye disease, previous trauma surgery, age-related macular degeneration...