You searched for "patient"
In vivo confocal microscopy, principles and use in keratitis Part 1: Principles
In 1968 Maurice introduced the concept of high powered specular microscopy, it was in that very year that the first scanning confocal microscope was proposed. Marvin Minsky developed the first confocal microscope in 1955 named the ‘double focusing scanning microscope’....Childhood glaucoma
When a child is given a diagnosis of glaucoma, the impact upon that child and their family is enormous; equivalent to the diagnosis of a cancer [14]. This article outlines the knowledge, techniques and approaches that offer solutions to the...Strengthening eye care services in Botswana through the Botswana-Addenbrooke’s Abroad VISION 2020 LINK
The VISION 2020 LINK between Botswana and Addenbrooke’s Abroad has been running for 10 years. With support from the VISION 2020 LINKS Programme two-way exchange visits were undertaken leading to the formation of the first formal international partnership under Addenbrooke’s...Use of off-the-shelf magnifying glasses as a cost-effective alternative for surgical loupes
Surgical loupes are an integral part of ophthalmic surgery on the ocular surface and in the periocular area. Available in different magnifications, they provide a clear view of the field of surgery which can greatly assist in identifying fine structures...In conversation with Dr Robert B Nussenblatt
Dr Robert B Nussenblatt is Chief of the Laboratory of Immunology at the National Eye Institute, an eminent ocular immunologist and an expert in clinical research design and conduct. Describe the success or relevance of the SUN project. The Standardization...
OCTA and pigment epithelium detachments
Yannuzzi et al. report on their study aiming to evaluate the ability of optical coherence tomography angiography (OCTA) to differentiate vascularised from nonvascularised pigment epithelium detachments (PEDs) using conventional imaging techniques, including fundus fluorescein angiography (FFA) and indocyanine green (ICG),...
CD40L activation of human RPE cells
Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...
Transfected RPE cells inhibit AMD in rats
Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...
Influence of FLEx and SMILE on corneal nerve density and ocular surface
This was a prospective study designed to compare the influence of femtosecond lenticule extraction (FLEx) and small incision lenticule extraction (SMILE) on the corneal nerve density and ocular surface for myopic correction. Thirty patients underwent bilateral lenticule extraction. One eye...Exploiting nature’s randomised trials of eye disease
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...
