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4137 results found

Keratoconus cone variants

This retrospective study examined correlation between three keratoconic parameters to further understand anatomy of keratoconic cones. Kmax and pachymetry of the thinnest point were obtained from the Pentacam scans. Decentration was calculated as distance from the corneal vertex to the...

Nystagmus surgery

This study used a questionnaire-based assessment of the qualitative experience of adults and parents of children who had 4-muscle tenotomy surgery for nystagmus. Pre and postoperative video recordings and visual acuity measurements were used to objectively assess the physical effect...

Screening for hydroxychloroquine retinopathy

The American Academy of Ophthalmology has updated the recommendations for screening for hydroxychloroquine retinopathy based on new scientific evidence that toxicity is not rare when hydroxychloroquine is used long-term, and that risk is dependent on the daily dose by weight....

Mental health issues linked with strabismus

The purpose of this study was to determine if adults with non-paralytic forms of strabismus are at elevated risk for developing mental illness. This was a population-based case-controlled study of 297 adults with new onset non-paralytic strabismus; 42.4% were male....

Amiodarone-associated optic neuropathy

This is a retrospective population-based cohort study to evaluate the risk of developing optic neuropathy from the use of amiodarone in Taiwan. Over a five-year period (2005-2009), there were 6175 amiodarone-treated patients with 24,700 patients taken as controls. After a...

Cataract surgery and circadian photoentrainment

The study authors sought to investigate the possible effects of circadian photoentrainment following cataract. This was a randomised clinical trial, where 76 eyes of 76 patients (with bilateral cataract) were randomised to blue-blocking or neutral intraocular lenses (IOLs). Outcome measures...

Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience

Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...

Risk factors for NTG in a young Korean population

Previously known ocular and systemic risk factors for normal tension glaucoma (NTG) include myopia, peripapillary atrophy, disc haemorrhage, migraine, obstructive sleep apnoea, thyroid disease and cerebral infarction. However, most NTG risk factor studies have examined patients aged 40 years and...

Surgical success rates in abducens palsy management

The aim of the study was to identify factors associated with surgical outcomes in isolated abducens palsy. To achieve this goal the authors reviewed the records of adult patients with abducens palsy who underwent strabismus procedures during a fourteen year...

Effect of preservative free fluoroquinolones on human corneal epithelial cells in vitro

Fluoroquinolones, including second generation (ofloxacin and ciprofloxacin), third generation (levofloxacin and tosufloxacin) and fourth generation (gatifloxacin and moxifloxacin), are a group of bactericidal agents used to treat multiple ocular infections. The third and fourth generation fluoroquinolones have enhanced Gram-positive activity...

Angle of deviation and psychological impact

This questionnaire-based prospective study using the Psychological Impact Questionnaire was designed to investigate whether the size of the angle of deviation, age, sex, presence of diplopia, visual acuity of the worse eye and direction of deviation are related to psychological...

Complement factor B polymorphism and the phenotype of early age-related macular degeneration

The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...