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Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

1 April 2016 | | Cataract and Refractive, Cornea / External Eye Disease, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

COVID-19: Pete’s Bogus Journey

6 April 2021 | | Ophthalmology, COVID-19
The author shares his personal experience of contracting coronavirus. I managed to body swerve COVID-19 for nine months. The Pfizer vaccine was being rolled out in my trust. I had my first inoculation booked in three weeks. I had survived...

Blinking blepharitis has a lot to answer for…

1 October 2015 | | Cornea / External Eye Disease
Never ignore the small things’…someone once said. There is no doubt blepharitis is one of the most common eye conditions encountered daily, but with the typical pressures of a busy outpatient department, the management of more obvious, sight-threatening conditions necessarily...

Strabismus and ocular motility, demystified

3 April 2024 | | Paediatric Ophthalmology / Strabismus, Optometry
I am a former orthoptist, now trained in medicine and working as a foundation doctor. In my previous work, I was frequently approached by ophthalmology trainees eager for guidance with strabismus and ocular motility. Drawing on my clinical experience, I...

Is it NAION… Now what?

3 April 2024 | | Neuro-Ophthalmology
Case presentation We present the case and discussion of a 46-year-old Caucasian male who complained of immediate reduced vision following complicated neck dissection including a total laryngopharyngectomy, free flap reconstruction for a T4N3 squamous cell carcinoma (SCC) of the left...

Time is vision in central retinal artery occlusion

4 August 2021 | | Ophthalmology, Retina / Uvea / Vitreous, Emergency Ophthalmology
Central retinal artery occlusion (CRAO) is a rare but devastating vascular episode that can have severe impact on vision. Treatment is very time-limited and needs to be initiated very quickly to salvage any vision. The majority of patients present to...

Meeting the needs of older patients in optics

1 February 2019 | | Cataract and Refractive, Optometry, Glaucoma, Retina / Uvea / Vitreous
Fiona Anderson discusses the important role of community-based eyecare practitioners in meeting the visual needs of ageing patients. It has been well documented that today we live for longer. Statistics show in 1997, around one in every six people (15.9%)...

A Multidisciplinary Approach to Neovascular Glaucoma in a Patient with Waldenström’s macroglobulinemia

1 December 2013 |
An 84-year-old Caucasian male attended eye casualty with a four month history of reduced vision, a dull ache and photophobia in both eyes. He had also reported dizziness, weakness and intermittent epistaxis in the nine months prior to presentation. There...

In vivo confocal microscopy, principles and use in keratitis Part 1: Principles

1 April 2018 | | Imaging, Cornea / External Eye Disease
In 1968 Maurice introduced the concept of high powered specular microscopy, it was in that very year that the first scanning confocal microscope was proposed. Marvin Minsky developed the first confocal microscope in 1955 named the ‘double focusing scanning microscope’....

The last three patients: dermatology (Patient Three)

3 August 2023 | | Dermatology
For the third and final reflection in this series (see Part 1 and Part 2), Professor Jonathan Rees recounts his experience of a patient with cancer who was failed by the NHS, and how their inadequate treatment illuminates some issues...

A paediatric case of central retinal artery occlusion following antibiotics and decompression surgery for orbital cellulitis

3 October 2022 | | Ophthalmology, Paediatric Ophthalmology / Strabismus
Orbital cellulitis is an ophthalmic emergency that warrants urgent management in the hospital setting [1]. This occurs more frequently in the paediatric population where it is often secondary to sinus infections. Delay in treatment could result in severe complications including...

Minimally Invasive Glaucoma Surgery: What options are there and when might they be considered?

25 March 2024 | | Glaucoma, ONLINE EXCLUSIVE ARTICLES
In recent years there has been a rapid expansion in a group of operations termed ‘minimally invasive’ or ‘micro invasive’ glaucoma surgery (MIGS). These options generally offer less significant IOP reduction, but with a more favourable safety profile when compared...